Septerna (NASDAQ:SEPN) Bolsa

SEPTERNA INC

Septerna

Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.

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Netflix sorprende con un aumento en suscriptores y mejores pronósticos. Descubre también los mayores ganadores y perdedores del premercado.

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Septerna Inc

Hilton Worldwide Holdings (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/HLT#NYSE">HLT</a>) has outperformed the market over the past 10 years by 4.2% on an annualized basis producing an average annual return of 14.53%. Currently, Hilton Worldwide Holdings has a market capitalization of $57.44 billion. 
Buying $100 In HLT: If an investor had bought $100 of HLT stock 10 years ago, it would be worth $384.99 today based on a price of $241.65 for HLT at the time of writing.
<h3>Hilton Worldwide Holdings's Performance Over Last 10 Years</h3>
<img src="https://www.benzinga.com/files/images/story/2025/1746657914_0.png" alt="comp_fig" />
Finally -- what's the point of all this? The key insight to take from this article is to note how much of a difference compounded returns can make in your cash growth over a period of time.
This article was generated by Benzinga's automated content engine and reviewed by an editor.

Here's How Much $100 Invested In Hilton Worldwide Holdings 10 Years Ago Would Be Worth Today

Earnings

Earnings Beats

UPDATE: Centrus Energy Q1 Adj. EPS $1.07, Sales $73.10M Beat $68.12M Estimate

Royal Gold (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/RGLD#NASDAQ">RGLD</a>) reported quarterly earnings of $1.51 per share which beat the analyst consensus estimate of $1.37 by 10.22 percent. This is a 65.93 percent increase over earnings of $0.91 per share from the same period last year. The company reported quarterly sales of $193.44 million which beat the analyst consensus estimate of $176.17 million by 9.80 percent. This is a 29.91 percent increase over sales of $148.90 million the same period last year.

RGLD

CORRECTION: Royal Gold Q1 Adj. EPS $1.51 Beats $1.37 Estimate, Sales $193.44M Beat $176.17M Estimate

Bloomin&#8217; Brands, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BLMN#NASDAQ">BLMN</a>) reported first quarter adjusted earnings per share of 59 cents on Wednesday, beating the <a target="_blank" href="https://www.benzinga.com/pressreleases/25/05/b45248079/bloomin-brands-announces-2025-q1-financial-results" rel="noreferrer noopener">analyst consensus estimate of 56 cents.</a>
Quarterly sales of $1.05 billion (down 1.8% year over year) outpaced the street view of $1.03 billion.
The decrease in total revenues was primarily due to the net impact of restaurant closures and openings and a decrease in comparable restaurant sales.
Also Read: <a target="_blank" href="https://www.benzinga.com/general/restaurants/25/04/45021992/us-restaurants-face-growth-hurdles-as-macro-headwinds-mount-says-analyst" rel="noreferrer noopener">US Restaurants Face Growth Hurdles As Macro Headwinds Mount, Says Analyst</a>
Adjusted operating income margin in the quarter under review contracted to 6.1% from 7.8% in the year-ago period.&nbsp;
Adjusted restaurant-level operating margin contracted to 13.9% from 15.5% a year ago, primarily due to lower revenues, higher operating, labor, and commodity costs, primarily due to inflation, and unfavorable product cost mix.
On April 23, the firm declared a quarterly cash dividend of $0.15 per share, payable on June 4, to stockholders of record at the close of business on May 20.
The company exited the quarter with cash and equivalents worth $57.691 million, and total debt of $917.610 million.
Outlook: Bloomin&#8217; Brands expects the second quarter adjusted EPS of $0.22 and $0.27, which is far lower than the $0.36 consensus estimate. The company reaffirmed its full-year 2025 adjusted EPS guidance of $1.20 to $1.40, compared to the $1.30 estimate.
&#8220;We are navigating a choppy macro environment and are leaning in to our abundant everyday value offerings. This is reflected in our current guidance,&#8221; said Mike Spanos, CEO.
Price Action: BLMN shares are trading higher by 0.76% to $7.990&nbsp;premarket at last check Friday.
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<li><a href="https://www.benzinga.com/general/restaurants/25/04/44907247/restaurant-sector-q1-volatilty-from-weather-inflation-analyst-lowers-price-targets" target="_blank" rel="noreferrer noopener">Restaurant Sector Q1 Volatility From Weather, Inflation — Analyst Lowers Price Targets</a></li>
</ul>
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BLMN

Outback Steakhouse Parent Bloomin Brands Q1 Earnings: Margin Contraction, High Debt, Weak Q2 Outlook

Black Hills (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BKH#NYSE">BKH</a>) affirms FY2025 GAAP EPS guidance from $4.00-$4.20 to $4.00-$4.20 vs $4.11 analyst estimate..

Black Hills Affirms FY2025 GAAP EPS Guidance of $4.00-$4.20 vs $4.11 Est

Black Hills (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BKH#NYSE">BKH</a>) reported quarterly earnings of $1.87 per share which missed the analyst consensus estimate of $1.93 by 3.11 percent. This is unchanged from the same period last year. The company reported quarterly sales of $805.20 million which beat the analyst consensus estimate of $706.08 million by 14.04 percent. This is a 10.85 percent increase over sales of $726.40 million the same period last year.

Earnings Misses

Black Hills Q1 EPS $1.87 Misses $1.93 Estimate, Sales $805.20M Beat $706.08M Estimate

You've probably heard that "comparison is the thief of joy." And sure, nobody wants to turn their finances into a competitive sport. But sometimes, curiosity gets the best of us—you just want to know how you measure up.
So, if you've ever wondered whether you're quietly keeping pace with your peers—or <a href="https://www.benzinga.com/24/11/41889242/are-you-in-the-top-10-heres-what-it-really-takes-to-make-the-cut-and-rank-among-the-richest">way ahead of the pack</a>—a breakdown of net worth benchmarks at every age might give you some insight.&nbsp;
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<h2 class="wp-block-heading">How Much Wealth Does the Typical American Household Have?</h2>
According to the <a href="https://www.federalreserve.gov/econres/scfindex.htm">Federal Reserve's latest data</a>, the median net worth for U.S. households is $192,900. That's the middle point—half of households have less than that, and half have more.
But the average net worth tells a different story, coming in at $1.06 million.
That number often throws people off. When people hear "average," they usually think it reflects what most individuals have. But in reality, the average gets pulled way up by a small number of very wealthy households. Most Americans have far less than that million-dollar figure. That's why financial experts focus on the median when they want to give a clearer picture of where the typical household stands.
Trending: <a href="https://www.benzinga.com/money/are-you-rich">Are you rich?</a> Here&#8217;s what Americans think you need to be considered wealthy.
<h2 class="wp-block-heading">What It Takes to Be in the Top 10% By Age</h2>
If you want to see how your net worth compares to the wealthiest 10% of Americans in your age group, here's what it takes:
<ul>
<li>Ages 18 to 34: You'd need at least $372,120</li>
<li>Ages 35 to 44: At least $1,042,300</li>
<li>Ages 45 to 54: At least $1,956,000</li>
<li>Ages 55 to 64: At least $2,960,900</li>
<li>Ages 65 to 74: At least $2,997,300</li>
<li>Ages 75 to 99: At least $2,681,400 </li>
</ul>
For example, if you're in your mid-50s, you'd need almost $3 million in net worth to be in the top 10% for your age.
<h2 class="wp-block-heading">Why Are These Numbers So High?</h2>
Several factors contribute to these steep benchmarks:
<ul>
<li>Home equity: Many in the top 10% <a href="https://www.benzinga.com/personal-finance/24/08/40610715/do-you-know-how-much-wealthier-homeowners-are-than-renters-spoiler-its-about-40x-more">own valuable real estate</a> that's appreciated significantly over time.</li>
<li>Investment growth: Long-term investing in stocks, retirement accounts, and other assets can compound wealth dramatically, especially for older age groups.</li>
<li>Business ownership: Some households <a href="https://advocacy.sba.gov/wp-content/uploads/2021/08/Small-Business-Facts-Business-Owner-Wealth.pdf?utm_source=chatgpt.com">build wealth through private businesses</a> or side ventures.</li>
<li>Inheritance and family wealth: In some cases, family money or inheritances push net worth figures higher.</li>
</ul>
It's also worth noting that wealth accumulation tends to speed up with age, as assets grow and debts like mortgages get paid down.
See Also: <a href="https://www.benzinga.com/money/gbr-savings-by-age">If You're Age 35, 50, or 60: Here&#8217;s How Much You Should Have Saved Vs. Invested By Now</a>
<h2 class="wp-block-heading">You Don't Necessarily Need to Be in the Top 10% to Feel Wealthy</h2>
Of course, reaching these numbers isn't the only way to define wealth. You might not need to be in the top 10% to feel wealthy—or even financially secure.
According to <a href="https://pressroom.aboutschwab.com/press-releases/press-release/2024/Schwab-Survey-Reveals-That-Americans-Think-It-Takes-2.5-Million-to-Be-Considered-Wealthy-in-2024/default.aspx">Charles Schwab's 2024 Modern Wealth Survey</a>, the average American believes it takes $2.5 million to feel "wealthy." That figure rose 14% from $2.2 million in 2023, largely because of inflation and rising living costs.
But the bar for simply feeling financially comfortable is much lower. Americans said around $778,000 would do it—down from $1 million the year before. That drop suggests many people are starting to value security and stability over extravagance, especially as economic uncertainty has made big, flashy wealth less of a priority.
<h2 class="wp-block-heading">Building Wealth Is a Long Game</h2>
If your net worth falls short of these benchmarks, you're not alone—and it doesn't mean you're financially behind. Wealth building usually takes time.&nbsp;
The important thing is focusing on consistent progress. Whether your goal is early retirement, financial independence, or simply peace of mind, building net worth is about <a href="https://www.benzinga.com/money/are-you-rich">creating freedom and security</a>, not chasing a number that fits someone else's definition of success.&nbsp;
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Image: Shutterstock

Personal Finance

Are You Richer Than Your Peers? Here's The Net Worth It Takes At Every Age To Be In The Top 10%

First BanCorp (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/FBP#NYSE">FBP</a>) has outperformed the market over the past 15 years by 6.6% on an annualized basis producing an average annual return of 17.68%. Currently, First BanCorp has a market capitalization of $3.28 billion. 
Buying $100 In FBP: If an investor had bought $100 of FBP stock 15 years ago, it would be worth $1,149.71 today based on a price of $20.12 for FBP at the time of writing.
<h3>First BanCorp's Performance Over Last 15 Years</h3>
<img src="https://www.benzinga.com/files/images/story/2025/1746657012_0.png" alt="comp_fig" />
Finally -- what's the point of all this? The key insight to take from this article is to note how much of a difference compounded returns can make in your cash growth over a period of time.
This article was generated by Benzinga's automated content engine and reviewed by an editor.

Here's How Much $100 Invested In First BanCorp 15 Years Ago Would Be Worth Today

Zillow Group Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/Z#NASDAQ">Z</a>) reported first-quarter financial results after the market close on Wednesday. Here&#8217;s a rundown <a href="https://www.benzinga.com/quote/Z">of the report</a>.
<ul>
<li>Q1 Revenue: $598 million, versus <a href="http://benzinga.com/quote/z/earnings">estimates</a> of $586.54 million</li>
</ul>
<ul>
<li>Q1 Adjusted EPS: 41 cents, versus estimates of 38 cents</li>
</ul>
Total revenue was up 13% year-over-year in the first quarter. The company noted that its quarterly revenue outperformed the residential real estate industry's year-over-year total transaction value growth.
Zillow ended the quarter with $1.6 billion in cash and cash equivalents after repurchasing $250 million worth of its common stock during the period.
"Our strong Q1 results surpassed our expectations and demonstrate how well we're executing. We are on track to meet our full-year 2025 goals, and we're well-positioned to deliver sustainable profitable growth," said Jeremy Wacksman, CEO of Zillow.
"As we expand our services and scale the housing super app across more markets, we are bringing more customers and real estate professionals together and making buying, selling, and renting easier for them, which is helping us grow both our revenue and profits."
Outlook: Zillow expects second-quarter revenue to be in the range of $635 million to $650 million versus estimates of $650.96 million, per <a href="http://pro.benzinga.com">Benzinga Pro</a>.
Z Price Action: <a href="http://benzinga.com/quote/z">Zillow shares</a> were down 5.42% after hours, trading at $64.20 at the time of publication on Wednesday, according to <a href="http://pro.benzinga.com">Benzinga Pro</a>.
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Photo: bilanol/Shutterstock.

After-Hours Center

Real Estate

Zillow Q1 Earnings Beat, Q2 Guidance Below Estimates, Shares Fall

Dine Brands Global Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/DIN#NYSE">DIN</a>) shares gained <a target="_blank" href="https://www.benzinga.com/movers" rel="noreferrer noopener">on Wednesday</a> after reporting the first-quarter earnings.
The company clocked <a target="_blank" href="https://www.benzinga.com/pressreleases/25/05/b45248092/dine-brands-global-inc-reports-first-quarter-2025-results" rel="noreferrer noopener">first-quarter FY25 revenue growth</a> of 4.1% year-on-year to $214.78 million, missing the analyst consensus estimate of $217.56 million.
The increase was primarily due to an increase in company restaurant sales, which were mainly attributable to the acquisition of 47 Applebee&#8217;s restaurants in the fourth quarter of 2024.
Adjusted EPS of $1.03 <a target="_blank" href="https://www.benzinga.com/earnings" rel="noreferrer noopener">missed the analyst consensus</a> estimate of $1.23.
Applebee&#8217;s year-over-year domestic comparable same-restaurant sales declined 2.2%&nbsp;while those of IHOP&#8217;s fell 2.7%.
General and Administrative expenses declined 1.7% to $52.2 million. Gross profit decreased 7.3% to $90.3 million with a gross margin of 42%.
Also Read: <a target="_blank" href="https://www.benzinga.com/general/restaurants/25/05/45177147/mcdonalds-stumbles-on-weak-traffic-despite-margin-gains-and-analyst-optimism" rel="noreferrer noopener">McDonald&#8217;s Stumbles On Weak Traffic, Despite Margin Gains And Analyst Optimism</a>
Adjusted EBITDA fell 10% to $54.7 million.
Operating cash flow for the quarter totaled $16.1 million, and adjusted free cash flow was $14.6 million. As of March 31, 2025, the company held $186.5 million in cash and equivalents.
&#8220;As we navigate the current operating environment, the fundamentals of our business remain strong, and since the second half of the quarter, we&#8217;re seeing steady improvement across sales, traffic, and our development pipeline,&#8221; said CEO John Peyton.
Outlook FY25: Applebee&#8217;s domestic system-wide comparable same-restaurant sales performance is expected to be negative 2% and positive 1%.
IHOP&#8217;s domestic system-wide comparable same-restaurant sales performance is expected to be negative 1% and positive 2%.
Dine Brands expects adjusted EBITDA of $235 million—$245 million and capital expenditures of $20 million—$30 million.
Price Action: DIN shares closed higher by 2.05% to $20.38 on Wednesday.
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<li><a href="https://www.benzinga.com/25/05/45237060/despite-nikes-executive-overhaul-ongoing-challenges-persist-says-analyst" target="_blank" rel="noreferrer noopener">Nike Revamps C-Suite, &#8216;Win Now&#8217; Strategy Faces Profit Pressure: Analyst</a></li>
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Photo by Tada Images via Shutterstock

What's Going On With Applebee Parent Dine Brands Stock On Wednesday?

Viemed Healthcare (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VMD#NASDAQ">VMD</a>) raises FY2025 sales outlook from $254.00 million-$265.00 million to $256.00 million-$265.00 million vs $260.00 million estimate.

Viemed Healthcare Raises FY2025 Sales Guidance from $254.00M-$265.00M to $256.00M-$265.00M vs $260.00M Est

Global Net Lease (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/GNL#NYSE">GNL</a>) affirms FY2025 FFO guidance from $0.90-$0.96 to $0.90-$0.96 vs $1.00 analyst estimate..

Global Net Lease Affirms FY2025 FFO Guidance of $0.90-$0.96 vs $1.00 Est

Enhabit (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/EHAB#NYSE">EHAB</a>) affirms FY2025 Adj EPS guidance from $0.41-$0.51 to $0.41-$0.51 vs $0.38 analyst estimate. Affirms FY2025 sales outlook from $1.05 billion-$1.08 billion to $1.05 billion-$1.08 billion vs $1.07 billion estimate.

EHAB

Enhabit Affirms FY2025 Adj EPS Guidance of $0.41-$0.51 vs $0.38 Est; Affirms FY2025 Sales Guidance of $1.05B-$1.08B vs $1.07B Est

Cerence (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CRNC#NASDAQ">CRNC</a>) reported quarterly earnings of $0.46 per share which beat the analyst consensus estimate of $0.14 by 228.57 percent. This is a 611.11 percent increase over losses of $(0.09) per share from the same period last year. The company reported quarterly sales of $78.00 million which beat the analyst consensus estimate of $75.41 million by 3.44 percent. This is a 15.00 percent increase over sales of $67.83 million the same period last year.

CRNC

Cerence Q2 EPS $0.46 Beats $0.14 Estimate, Sales $78.00M Beat $75.41M Estimate

Axon Enterprise Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AXON#NASDAQ">AXON</a>) shares are rising in after-hours Wednesday after the company beat first-quarter estimates and raised its <a href="https://www.benzinga.com/pressreleases/25/05/n45265409/axon-reports-q1-2025-revenue-of-604-million-up-31-year-over-year">full-year guidance</a>.
Q1 Earnings: Axon reported first-quarter revenue of $603.63 million, beating analyst estimates of $583.76 million. The company reported first-quarter adjusted earnings of $1.41 per share, beating analyst estimates of $1.27 per share, according to <a href="http://pro.benzinga.com">Benzinga Pro</a>.
Total revenue was up 31% year-over-year. Axon&#8217;s first-quarter results were led by strength in Software and Services, which generated&nbsp;$263 million&nbsp;in revenue, up&nbsp;39%&nbsp;year-over-year.
Axon raised its full-year guidance from a range of $2.55 billion to $2.65 billion to a new range of $2.6 billion to $2.7 billion versus estimates of $2.62 billion.
&#8220;Strong alignment with our customers, expanding vertical applications and sustained product innovation underpin Axon&#8217;s increased&nbsp;outlook&nbsp;for the remainder of the year,&#8221; the company said.
AXON Price Action: <a href="http://benzinga.com/quote/axon">Axon Enterprise shares</a> were up 4.68% at $630 in extended trading at the time of publication Wednesday, according to <a href="http://pro.benzinga.com">Benzinga Pro</a>.
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This illustration was generated using artificial intelligence via Midjourney.

AXON

Axon Enterprise Stock Pops On Q1 Earnings: Key Details

Inspirato (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ISPO#NASDAQ">ISPO</a>) affirms FY2025 sales outlook from $235.00 million-$255.00 million to $235.00 million-$255.00 million vs $267.50 million estimate.

ISPO

Inspirato Affirms FY2025 Sales Guidance of $235.00M-$255.00M vs $267.50M Est

Kyndryl Hldgs (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/KD#NYSE">KD</a>) sees FY2026 sales of $15.208 billion vs $15.14 billion analyst estimate.

Kyndryl Hldgs Sees FY2026 Revenue to be up by 1% YoY

RBC Bearings (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/RBC#NYSE">RBC</a>) has outperformed the market over the past 15 years by 5.78% on an annualized basis producing an average annual return of 16.87%. Currently, RBC Bearings has a market capitalization of $10.76 billion. 
Buying $1000 In RBC: If an investor had bought $1000 of RBC stock 15 years ago, it would be worth $10,291.73 today based on a price of $342.20 for RBC at the time of writing.
<h3>RBC Bearings's Performance Over Last 15 Years</h3>
<img src="https://www.benzinga.com/files/images/story/2025/1746656111_0.png" alt="comp_fig" />
Finally -- what's the point of all this? The key insight to take from this article is to note how much of a difference compounded returns can make in your cash growth over a period of time.
This article was generated by Benzinga's automated content engine and reviewed by an editor.

$1000 Invested In RBC Bearings 15 Years Ago Would Be Worth This Much Today

Smartstop Self Storage (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SMA#NYSE">SMA</a>) reported quarterly earnings of $0.41 per share. This is a 2.5 percent increase over earnings of $0.40 per share from the same period last year. The company reported $65.45 million in sales this quarter. This is a 14.74 percent increase over sales of $57.04 million the same period last year.

Smartstop Self Storage Q1 FFO $0.41 Up From $0.40 YoY, Sales $65.45M Up From $57.04M YoY

goeasy (TSX:<a class="ticker" href="https://www.benzinga.com/stock/GSY#TSX">GSY</a>) affirms FY2025 sales outlook from $1.62 billion-$1.82 billion to $1.62 billion-$1.82 billion.

TSX:GSY

goeasy Affirms FY2025 Sales Guidance of $1.62B-$1.82B

Press Releases

Septerna Announces Discontinuation of SEP-786 Phase 1 Clinical Trial and Plans to Advance Next-Generation Oral Small Molecule PTH1R Agonist

Legal

Septerna, Inc. Investors: Company Investigated by the Portnoy Law Firm

Kirby McInerney LLP Announces Investigation Against Septerna, Inc. (SEPN) on Behalf of Investors

SEPTERNA ALERT: Bragar Eagel & Squire, P.C. is Investigating Septerna, Inc. on Behalf of Septerna Stockholders and Encourages Investors to Contact the Firm

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