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UPDATED: Nov 13, 2025

Stock Analysis

OPT Logo
Opthea
NASDAQ:OPT
Market Cap:
566.00M
P/E Ratio:
0.0000
Avg Value:
$4.05
Year Range:
$1.79 - $6.30
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General Information
Opthea Ltd is engaged in researching and developing novel therapeutic products that target Vascular Endothelial Growth Factors (VEGF) C, D, and R3.

The Group operates in one industry and two geographical areas, namely biotechnology and healthcare, with operations in Australia and the United States. The company focuses on developing biological therapeutics for eye diseases and is currently developing a novel biologic therapy, OPT-302, for the treatment of eye conditions. Its products are based on an intellectual property portfolio covering VEGF-C, VEGF-D, and VEGF Receptor-3 targets, aimed at treating diseases associated with blood and lymphatic vessel growth and vascular leakage.

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Opthea (OPT) Stock Graph
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How We Grade Opthea (OPT)

We grade stocks based on past performance, their future growth potential, intrinsic value, dividend history, and overall financial health.

The chart below shows how we grade Opthea (OPT) across the board compared to its closest peers.

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Benzinga Edge Rankings

Benzinga Edge stock rankings give you four critical scores to help you identify the strongest and weakest stocks to buy and sell.

5
Peer Ratings

See how Opthea compares to its peers in these key performance metrics from Benzinga Rankings.

Top Peers
Value
Quality
Growth
Momentum
Short
Medium
Long
RNAAvidity Biosciences
0
0
0
93.12
EXELExelixis
51.93
87.46
0
58.41
IONSIonis Pharmaceuticals
0
0
0
94.33
MDGLMadrigal Pharmaceuticals
0
0
0
91.42
Short: price trend over the last couple of months
Medium: price trend over the last couple of quarters
Long: price trend over the past year
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Benzinga Rankings give you vital metrics on any stock – anytime.
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Past Performance
How has Opthea (OPT) performed over the past 5 years?

The two main factors that we consider when analyzing past performance is overall return and volatility

Using these two metrics, we can determine if this stock gave its investors enough return for the risk that they took on by owning it. This is measured by the sharpe ratio, which has been used as a primary measure of risk/reward trade-off for almost 60 years.

This ratio can be interpreted as the amount of return an investor has received for the amount of risk that they took on by owning the stock over that timeframe.

Opthea (OPT) sharpe ratio over the past 5 years is -0.5433 which is considered to be below average compared to the peer average of 0.7355