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UPDATED: Nov 10, 2025

Stock Analysis

Metsera
NASDAQ:MTSR
$83.18
$1.63 |2.00%
Day Range:
$80.30 - $83.86
Market Cap:
7.43B
P/E Ratio:
0.0000
Avg Value:
$48.08
Year Range:
$12.30 - $83.86
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General Information
Metsera Inc is a clinical-stage biotechnology company developing next-generation injectable and oral nutrient-stimulated hormone (NuSH) analog peptides to treat obesity, overweight, and related conditions.

The Company has developed and is implementing proprietary methods and platform technologies to advance a broad, scalable, and combinable portfolio of injectable and oral NuSH analog peptides with the potential to address not only the limitations of approved therapies but also many of the anticipated limitations of next-generation therapies in development. The Company uses its proprietary MINT peptide library of NuSH analog peptides alongside its Half-life Augmentation by Lipid Optimization half-life extending platform.

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Metsera (MTSR) Stock Graph
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How We Grade Metsera (MTSR)

We grade stocks based on past performance, their future growth potential, intrinsic value, dividend history, and overall financial health.

The chart below shows how we grade Metsera (MTSR) across the board compared to its closest peers.

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Benzinga Edge Rankings

Benzinga Edge stock rankings give you four critical scores to help you identify the strongest and weakest stocks to buy and sell.

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Peer Ratings

See how Metsera compares to its peers in these key performance metrics from Benzinga Rankings.

Top Peers
Value
Quality
Growth
Momentum
Short
Medium
Long
CYTKCytokinetics
0
0
0
86.86
CAICaris Life Sciences
0
0
0
0
MRUSMerus
0
0
0
94.56
HALOHalozyme Therapeutics
18.26
87.65
0
54.14
Short: price trend over the last couple of months
Medium: price trend over the last couple of quarters
Long: price trend over the past year
Stock Score Locked: Want to See it?
Benzinga Rankings give you vital metrics on any stock – anytime.
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Future Growth
Our estimate of future price growth is based on an aggregation of 2 analyst ratings over the past 3 months and their 12-month price targets.

Below, you can see that analysts are estimating a 12-month price target range of $50.00 - $77.00 with an average of $61.33

-13.08%
Expected movement for Metsera (MTSR) over the next 12 months
Based on these rankings

Recent Ratings for Metsera (MTSR)

Leerink Partners
Date:
Sep 24, 2025
Action:
Downgrades
Prev. Target:
$77.00
New Target:
$57.00
B of A Securities
Date:
Aug 28, 2025
Action:
Maintains
Prev. Target:
$45.00
New Target:
$50.00
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Past Performance
How has Metsera (MTSR) performed over the past 5 years?

The two main factors that we consider when analyzing past performance is overall return and volatility

Using these two metrics, we can determine if this stock gave its investors enough return for the risk that they took on by owning it. This is measured by the sharpe ratio, which has been used as a primary measure of risk/reward trade-off for almost 60 years.

This ratio can be interpreted as the amount of return an investor has received for the amount of risk that they took on by owning the stock over that timeframe.

Metsera (MTSR) sharpe ratio over the past 5 years is 0.8410 which is considered to be above average compared to the peer average of 0.5490

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Analyzing Metsera (MTSR) Recent Options Activity
Below, you can see the trend in options sentiment over the past 30 days.

Based on our data, MTSR's options trades have recently carried more negative sentiment than positive.