| Sep 22, 2026 | Taylor Brian Slingsby | DIRECTOR | SELL | 104.320K | $28.81 | $3.0M |
| Sep 21, 2026 | Eric Warren | CHIEF COMMERCIAL OFFICER | SELL-OPTIONS | — | $20.68 | $111K |
| Sep 15, 2026 | Daphne Karydas | DIRECTOR | SELL-OPTIONS | — | $20.30 | $50K |
| Aug 21, 2026 | Eric Warren | CHIEF COMMERCIAL OFFICER | SELL-OPTIONS | — | $19.61 | $95K |
| Aug 10, 2026 | Malcom David Rodman | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $21.55 | $24K |
| Jul 21, 2026 | Eric Warren | CHIEF COMMERCIAL OFFICER | SELL-OPTIONS | — | $20.06 | $101K |
| Jul 17, 2026 | Malcom David Rodman | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $20.98 | $5K |
| Jul 13, 2026 | Jon Congleton | CHIEF EXECUTIVE OFFICER | SELL | 10.700K | $27.24 | $291K |
| Jul 13, 2026 | Malcom David Rodman | CHIEF MEDICAL OFFICER | SELL | 6.349K | $17.28 | $454K |
| Jul 9, 2026 | Malcom David Rodman | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $23.15 | $31K |
| Jun 30, 2026 | Jon Congleton | CHIEF EXECUTIVE OFFICER | SELL | 75.000K | $26.14 | $2.0M |
| Jun 26, 2026 | Eric Warren | CHIEF COMMERCIAL OFFICER | SELL-OPTIONS | — | $19.57 | $1.3M |
| Jun 17, 2026 | Daphne Karydas | DIRECTOR | SELL-OPTIONS | — | $18.51 | $39K |
| Jun 15, 2026 | Malcom David Rodman | CHIEF MEDICAL OFFICER | SELL | 6.348K | $18.37 | $248K |
| Jun 10, 2026 | Malcom David Rodman | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $14.54 | $165K |
| May 18, 2026 | Malcom David Rodman | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $21.50 | $5K |
| May 11, 2026 | Malcom David Rodman | CHIEF MEDICAL OFFICER | SELL | 6.349K | $18.68 | $516K |
| Apr 17, 2026 | Malcom David Rodman | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $23.38 | $7K |
| Apr 13, 2026 | Malcom David Rodman | CHIEF MEDICAL OFFICER | SELL | 6.348K | $17.08 | $446K |
| Apr 13, 2026 | Jon Congleton | CHIEF EXECUTIVE OFFICER | SELL | 15.730K | $26.83 | $422K |
| Apr 9, 2026 | Malcom David Rodman | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $21.69 | $25K |
| Mar 31, 2026 | Jon Congleton | CHIEF EXECUTIVE OFFICER | SELL | 75.000K | $26.27 | $2.0M |
| Mar 31, 2026 | Daphne Karydas | DIRECTOR | SELL-OPTIONS | — | $18.51 | $39K |
| Mar 27, 2026 | RA CAPITAL MANAGEMENT LP, RA Capital Healthcare Fund LP, RA Capital Nexus Fund III LP, Peter Kolchinsky, Rajeev Shah | DIRECTOR | BUY | 369.000K | $23.75 | $8.8M |
