El interés en corto de BioCryst Pharma da a los inversores una idea del grado en que los inversores apuestan por la caída de las acciones de BioCryst Pharma. Los datos de interés en corto se actualizan cada dos semanas.

BioCryst Pharma (NASDAQ:BCRX) Bolsa, Informe de interés en corto

BioCryst Pharma

BioCryst Pharmaceuticals Inc is a biotechnology company involved mainly in the research and development of novel small-molecule drugs, to block key enzymes involved in infectious and inflammatory diseases. Biocryst's research is based on multiple scientific disciplines like biology, computer modeling, and medicinal chemistry. Its products and candidates target the following therapeutic areas: acute uncomplicated influenza; uncomplicated seasonal influenza; hereditary angioedema; filoviruses, including the Ebola and Marburg viruses; and oncology.

BioCryst Pharmaceuticals, Inc. - Common Stock

BioCryst Pharmaceuticals Inc

Evercore ISI Group analyst Liisa Bayko maintains BioCryst Pharma (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BCRX#NASDAQ">BCRX</a>) with a Outperform and raises the price target from $10 to $12.

News

Price Target

Analyst Ratings

BCRX

Evercore ISI Group Maintains Outperform on BioCryst Pharma, Raises Price Target to $12

Needham analyst Serge Belanger maintains BioCryst Pharma (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BCRX#NASDAQ">BCRX</a>) with a Buy and raises the price target from $14 to $15.

Needham Maintains Buy on BioCryst Pharma, Raises Price Target to $15

BioCryst Says ORLADEYO Net Revenue Expected Between $515M-$535M In 2025, Total revenue (Including RAPIVAB) Will Be $540M-$560M

BioCryst Pharmaceuticals, Inc.&nbsp;(Nasdaq:&nbsp;BCRX) today announced that the Health Services Executive (HSE) in Ireland has recommended ORLADEYO&#xAE;&nbsp;(berotralstat) for the routine prevention of recurrent attacks of hereditary angioedema (HAE) in eligible patients 12 years and older. With this recommendation, HAE patients in Ireland will have access to the first oral, once-daily therapy for the reduction of recurrent HAE attacks.
"The positive HSE recommendation of ORLADEYO&nbsp;broadens access to modern prophylaxis, providing greater choice for prescribing physicians and potentially a better quality of life for HAE patients in Ireland," said Charlie Gayer, chief commercial officer of BioCryst.
The HSE decision in Ireland follows the European Commission marketing authorization of ORLADEYO in April 2021. To date, ORLADEYO is licensed in 44 countries.

Government

Regulations

BioCryst's ORLADEYO Gets Ireland's Approval: Expanding Access to Once-Daily HAE Therapy

RBC Capital analyst Brian Abrahams reiterates BioCryst Pharma (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BCRX#NASDAQ">BCRX</a>) with a Outperform and maintains $10 price target.

Reiteration

RBC Capital Reiterates Outperform on BioCryst Pharma, Maintains $10 Price Target

Needham analyst Serge Belanger reiterates BioCryst Pharma (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BCRX#NASDAQ">BCRX</a>) with a Buy and maintains $14 price target.

Needham Reiterates Buy on BioCryst Pharma, Maintains $14 Price Target

Barclays analyst Gena Wang maintains BioCryst Pharma (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BCRX#NASDAQ">BCRX</a>) with a Equal-Weight and raises the price target from $7 to $8.

Barclays Maintains Equal-Weight on BioCryst Pharma, Raises Price Target to $8

<h3>Gainers</h3>
<ul>
<li>Nuwellis (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NUWE#NASDAQ">NUWE</a>) shares rose 127.9% to $3.1 during Monday's regular session. The company's market cap stands at $5.7 million. </li>
<li>Singular Genomics Sys (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/OMIC#NASDAQ">OMIC</a>) stock moved upwards by 58.24% to $21.3. The company's market cap stands at $53.1 million. </li>
<li>Neurogene (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NGNE#NASDAQ">NGNE</a>) shares increased by 44.04% to $66.36. The market value of their outstanding shares is at $862.2 million. </li>
<li>Integra Lifesciences (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/IART#NASDAQ">IART</a>) stock rose 24.27% to $23.96. The company's market cap stands at $1.8 billion. As per the press release, Q3 earnings came out today. </li>
<li>BioSig Technologies (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BSGM#NASDAQ">BSGM</a>) stock rose 23.42% to $1.37. The market value of their outstanding shares is at $22.3 million. </li>
<li>Disc Medicine (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/IRON#NASDAQ">IRON</a>) shares moved upwards by 22.19% to $57.59. The market value of their outstanding shares is at $1.7 billion. </li>
</ul>
<h3>Losers</h3>
<ul>
<li>XTL Biopharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/XTLB#NASDAQ">XTLB</a>) shares decreased by 15.8% to $1.98 during Monday's regular session. The company's market cap stands at $10.7 million. </li>
<li>BioCryst Pharma (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BCRX#NASDAQ">BCRX</a>) stock declined by 15.6% to $7.12. The company's market cap stands at $1.4 billion. The company's, Q3 earnings came out today. </li>
<li>Third Harmonic Bio (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/THRD#NASDAQ">THRD</a>) shares declined by 15.57% to $12.1. The market value of their outstanding shares is at $497.2 million. </li>
<li>Cadrenal Therapeutics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CVKD#NASDAQ">CVKD</a>) shares decreased by 15.52% to $14.87. The market value of their outstanding shares is at $22.2 million. </li>
<li>Tevogen Bio Holdings (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TVGN#NASDAQ">TVGN</a>) stock declined by 13.5% to $2.05. The company's market cap stands at $349.8 million. </li>
<li>Journey Medical (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/DERM#NASDAQ">DERM</a>) stock decreased by 13.3% to $5.35. The market value of their outstanding shares is at $110.8 million. 
See Also: <a href="http://www.benzinga.com/money/best-healthcare-stocks/" title="www.benzinga.com/money/best-healthcare-stocks/">www.benzinga.com/money/best-healthcare-stocks/</a></li>
</ul>
This article was generated by Benzinga's automated content engine and reviewed by an editor.

Movers

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XTLB

12 Health Care Stocks Moving In Monday's Intraday Session

WIIM

BioCryst Pharma shares are trading lower following mixed Q3 financial results.

Financial Outlook for 2024
Based on the strength of patient demand for ORLADEYO seen in the third quarter, and expected continued strength in the fourth quarter, the company is adjusting its outlook for full year 2024 global net ORLADEYO revenue to be between $430 million and $435 million (top end of prior range) and introducing full-year 2024 total revenue guidance of between $443 and $448 million based on additional 2024 RAPIVAB revenue.

Guidance

BioCryst Adjusts ORLADEYO Revenue Guidance To $430M-$435M, Sees Total Product Revenue Of $443M-$448M

BioCryst Pharma (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BCRX#NASDAQ">BCRX</a>) reported quarterly losses of $(0.07) per share which missed the analyst consensus estimate of $(0.06) by 16.67 percent. This is a 63.16 percent increase over losses of $(0.19) per share from the same period last year. The company reported quarterly sales of $117.085 million which beat the analyst consensus estimate of $112.503 million by 4.07 percent. This is a 34.98 percent increase over sales of $86.742 million the same period last year.

Earnings

Earnings Beats

Earnings Misses

BioCryst Pharma Q3 2024 GAAP EPS $(0.07) Misses $(0.06) Estimate, Sales $117.085M Beat $112.503M Estimate

Biotech

General

BioCryst Highlights Real-World Data Showing High Adherence And Sustained Efficacy Of ORLADEYO For Hereditary Angioedema; Significant Reduction In HAE Attack Rates And Strong Patient Preference For Oral Therapy Reported

<a href="https://www.globenewswire.com/Tracker?data=thMGJcWW8AjTyfCdJD1xEBtP9-UfOazyoISk64JnA5BjVTgverx4tk3EokPzyivmSOugN4h9qO92NeHgMVH1owl-X3tJ-hIrPYB6qZ4UkYU=">BioCryst Pharmaceuticals, Inc.</a> (Nasdaq:&nbsp;BCRX) today announced new real-world evidence on the use of oral, once-daily ORLADEYO&#xAE; (berotralstat) demonstrating that patients with hereditary angioedema (HAE) in the United States experience significant reductions in healthcare resource utilization (HRU), including significant reductions in hospitalizations, emergency room visits and use of on-demand therapies, after beginning treatment with ORLADEYO. &nbsp;
The study will be presented in a poster at the Academy of Managed Care Pharmacy (AMCP) Nexus 2024 national meeting, which is being held in Las Vegas from October 14-17, 2024.
"Our interrogation of claims data builds upon previously reported findings demonstrating that ORLADEYO not only has a favorable impact on the lives of patients with HAE – but the broader healthcare system, as well. Here, our analysis reveals that significant reductions in healthcare resource utilization are achieved across multiple outcomes – such as reductions in hospitalizations and medical visits, including those related to HAE attacks. Decreases in on-demand treatment were also observed. Taken together, our investigation provides promising real-world evidence which supports ORLADEYO's clinical and financial value as a prophylactic therapy for HAE," said Sandra Christiansen, MD, professor of medicine and director of translational research at the US HAEA Angioedema Center at the University of California, San Diego.
The poster Healthcare Resource Utilization among Patients Initiating Berotralstat for the Long Term Prophylaxis of Hereditary Angioedema in the United States (#D20) detailed findings from a retrospective pre-post study that featured analysis of administrative U.S. claims data of patients with HAE in the United States. The analysis focused on eligible patients enrolled in commercial and public health plans who initiated ORLADEYO between December 2020 and December 2022 who had a baseline of at least six months of continuous health plan enrollment prior to starting ORLADEYO&nbsp;(n=260).
<ul>
<li>Significant reductions in HRU were observed in the overall study population following initiation of ORLADEYO (p&lt;0.05), including in: 
<ul>
<li>All-cause hospitalizations (34 percent reduction) and outpatient or emergency room visits (14 percent reduction).</li>
<li>Angioedema-related hospitalizations (52 percent reduction) and outpatient or emergency room visits (44 percent reduction). &nbsp;</li>
</ul>
</li>
<li>Significant reductions in HAE attack-related HRU were also observed (p&lt;0.05), including in: 
<ul>
<li>HAE attack-related visits (51 percent reduction), driven by significant decreases in hospitalization (60 percent) and outpatient or emergency room visits (50 percent).</li>
<li>Reduction in HAE attack-related visits were observed when stratified by body location of the attack, including in the head and upper airways (48 percent reduction), gastrointestinal system (58 percent reduction) and unspecified locations (52 percent reduction).</li>
<li>Additionally, a decrease in use of on-demand therapies administered by a healthcare professional was observed (39 percent reduction) among patients who previously received on-demand treatment.</li>
</ul>
</li>
</ul>

BioCryst's ORLADEYO Reduces Hospital Visits and Emergency Care for Hereditary Angioedema Patients, Study Shows

Health Care

BioCryst Pharmaceuticals Has Enrolled The First Participant In A Phase 1 Trial Evaluating BCX17725 For Netherton Syndrome, A Genetic Disorder Affecting The Skin, Hair, And Immune System; Initial Data Expected By End Of 2025

Contracts

The Us Department Of Health And Human Services Has Awarded BioCryst Pharmaceuticals Up To A $69M Contract For The Procurement Of Up To 95,625 Doses Over A Five-year Period Of Rapivab (Peramivir Injection) For Influenza

BioCryst Pharmaceuticals Has Completed Negotiations With The Pan-Canadian Pharmaceutical Alliance For Orladeyo (Berotralstat), Which Is Approved In Canada For The Routine Prevention Of Attacks Of Hereditary Angioedema For Patients 12 Years Of Age And Older

<a href="https://www.globenewswire.com/Tracker?data=7XUiJbtvdrsn6XxPZLvhx4I22y-w7FTXimBG_O8iw4lOkc10Ojls36Kl3lM2i5K9PWZiuCOFzYW-AR3rKYGVxlDj1CLihCxmk4CrjN3knVye720WpsxZTuGQ6vqru2fbimAvQoqw7Y4tRAi9o9KXJf1ugb6PXVnzfdI7hdFOb0nvo51qlaEHL_jFJ7s20yy8YFW7moeB5w--sUIjrglDrS9axU1AIYk5ywudjhGpunM4knWngdq-Si9LmJVz7U0BYNGjfshIiOZEI1Zp84IZhQ==">BioCryst Pharmaceuticals, Inc.</a>&nbsp;(Nasdaq:&nbsp;BCRX) today announced the presentation of six posters, including the first interim real-word evidence from the APeX-N trial, and new data highlighting the value of shared decision making (SDM) between healthcare providers (HCPs) and their hereditary angioedema (HAE) patients to provide optimal patient outcomes.
The company is presenting the posters at the 7th Bradykinin Symposium in Berlin from September 5-6, 2024.
<ul>
<li>APeX-N interim results: Oral berotralstat for HAE prophylaxis in Europe</li>
<li>HCP and patient perspectives: HAE long-term prophylaxis and shared decision-making</li>
<li>Adverse health outcomes and perspectives of androgen use in HAE</li>
<li>Evaluation of adherence to berotralstat in patients with hereditary angioedema</li>
<li>Tolerability and effectiveness of berotralstat for long-term prophylaxis in HAE</li>
<li>Effectiveness and safety of berotralstat in HAE with normal C1-inhibitor</li>
</ul>
APeX-N interim results
APeX-N is a European multi-center observational study assessing the safety (primary objective), effectiveness and quality of life (secondary objectives) of berotralstat 150 mg in routine clinical use. This interim analysis included 56 patients from the United Kingdom, France, Germany and Sweden.
Non-serious gastrointestinal adverse events were reported in 12.5 percent of patients. Seven percent (n=4) of patients discontinued treatment (three due to unsatisfactory response, one to participate in a clinical trial). One patient had a severe HAE attack but continued treatment.
"These initial data from APeX-N in Europe reinforce and closely replicate the clinical trial and real-world evidence of berotralstat as the first oral prophylaxis for HAE," said Dr. Sorena Kiani, consultant immunologist at Royal Free London NHS Foundation.
HCP and patient perspectives: HAE long-term prophylaxis and shared decision-making
This study, conducted in Germany, explored the dynamics between HCPs and patients in HAE management, identifying barriers to SDM and strategies to improve it. Ten HCPs participated in 60 minute interviews and simulated patient consultations. Eight HAE patients participated in 30 minute interviews. Participants then convened in structured focus groups to discuss their findings.
The participants identified a need for enhanced HCP awareness of patient perspectives, more comprehensive HCP-patient conversations and improved education about HAE treatment management.
"The findings from this study support the need for further insights to develop future guidance and HAE management strategies to facilitate successful shared decision making and improved patient quality of life," said Dr. Emel Aygören-Pürsün, department for children and adolescents, University Hospital Frankfurt, Germany.

BioCryst Presents Results on HAE Treatment and Patient Care at Global Symposium

JMP Securities analyst Jonathan Wolleben maintains BioCryst Pharma (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BCRX#NASDAQ">BCRX</a>) with a Market Outperform and raises the price target from $15 to $16.

JMP Securities Maintains Market Outperform on BioCryst Pharma, Raises Price Target to $16

Barclays analyst Gena Wang maintains BioCryst Pharma (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BCRX#NASDAQ">BCRX</a>) with a Equal-Weight and raises the price target from $6 to $7.

Barclays Maintains Equal-Weight on BioCryst Pharma, Raises Price Target to $7

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BioCryst reports inducement grants under Nasdaq listing rule

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BioCryst (BCRX) Receives a Buy from RBC Capital

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BioCryst sees FY25 ORLADEYO revenue between $515M-$535M

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BioCryst Projects Strong Revenue Growth in 2024-2025

BioCryst releases preliminary 2024 results, 2025 guidance

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BioCryst: Strong Sales Performance and Future Growth Projections Lead to Buy Rating

Needham analyst Serge Belanger raised the firm's price target on BioCryst (BCRX) to $15 from $14 and keeps a Buy rating on the shares. The company ...

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