El interés en corto de Prelude Therapeutics da a los inversores una idea del grado en que los inversores apuestan por la caída de las acciones de Prelude Therapeutics. Los datos de interés en corto se actualizan cada dos semanas.

Prelude Therapeutics (NASDAQ:PRLD) Bolsa, Informe de interés en corto

Prelude Therapeutics

Prelude Therapeutics Incorp is a clinical-stage precision oncology company focused on discovering and developing small molecule therapies optimized to target the key driver mechanisms in cancers with high unmet needs. The company's pipeline includes four candidates currently in clinical development: PRT1419, a potent, selective inhibitor of MCL1; PRT2527, a potent and selective CDK9 inhibitor, PRT3645, a next-generation CDK4/6 inhibitor, and PRT3789 a first-in-class SMARCA2/BRM protein degrader.

Prelude Therapeutics Incorporated - Common Stock

Prelude Therapeutics Inc

Moderna, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MRNA#NASDAQ">MRNA</a>) and Cenra Healthcare, the sales and marketing arm of Cenra Inc., today announced that the companies have entered into a joint agreement regarding the co-promotion of Moderna's mRNA respiratory vaccine portfolio in Taiwan, including Moderna's COVID-19 vaccine, Spikevax&#xAE;.
Under the agreement, Moderna will manufacture and distribute its mRNA respiratory vaccines. Cenra Healthcare will engage in promotion and execute medical education activities to ensure broad access to Moderna's mRNA respiratory portfolio across Taiwan. The agreement has an initial term until July 31, 2027, and no further details on the financial terms of the deal are being disclosed.

Government

News

Regulations

MRNA

Reported Earlier, Moderna and Cenra Healthcare Join Forces to Promote COVID-19 and Respiratory Vaccines in Taiwan

Over the years, billionaire investor Mark Cuban and former President Donald Trump have shared a multifaceted relationship. Their complicated and rather chaotic history started as being TV rivals.
What Happened: In 2004, Cuban&#8217;s &#8220;The Benefactor&#8221; and Trump&#8217;s &#8220;The Apprentice&#8221; began airing. While The Apprentice ran for 15 seasons, Cuban&#8217;s The Benefactor was canceled after just six episodes.
At the time, in a blog post titled &#8220;Thank you, Donald,&#8221; Cuban expressed his frustration after Trump told the Chicago Sun-Times, &#8220;You&#8217;ll have 100 people trying to do shows a little bit like us.&#8221;
&#8220;Let's get some things cleared up in case anyone is confused. The Benefactor is going to be nothing like The Apprentice. Why? Because, Donald, we are not alike in any way,&#8221; the &#8220;Shark Tank&#8221; star stated.
In the same blog post, Cuban reminisced about meeting Trump at a 1999 Super Bowl party at Mar-a-Lago, after which Trump invited him to meet in New York.
According to the billionaire, the former President&#8217;s office walls were completely covered with photos and magazine covers featuring him.
See Also: <a href="https://www.benzinga.com/general/politics/24/09/41079936/shaq-called-trump-a-straight-up-guy-before-presidency-i-think-he-just-says-it-wrong-but-did-the-?itm_source=parsely-api" target="_blank" rel="noreferrer noopener">Shaq Called Trump &#8216;A Straight-Up Guy&#8217; Before Presidency, &#8216;I Think He Just Says It Wrong&#8217;</a>
&#8220;After leaving your office, I promised myself that if I ever got liquid and had an obscene amount of money in the bank, I would make a point not to remind myself and everyone else around me of it every minute of every day unlike you,&#8221; he said, adding, &#8220;I guess our definition of success is just completely different.&#8221;
Following Cuban&#8217;s blog post, Trump stated he didn&#8217;t recall meeting him. In response, Cuban wrote a follow-up post titled &#8220;Of course you don&#8217;t remember, Donald.&#8221;
<figure class="wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter"> 
<div class="wp-block-embed__wrapper">
<blockquote class="twitter-tweet" data-width="500" data-dnt="true">A history of Donald Trump and Mark Cuban&#39;s &#39;love-hate relationship&#39; <a href="https://t.co/wDeYT6En1y">https://t.co/wDeYT6En1y</a> via <a href="https://twitter.com/BusinessInsider?ref_src=twsrc%5Etfw">@businessinsider</a>
&mdash; Mark Cuban (@mcuban) <a href="https://twitter.com/mcuban/status/1840871506835902749?ref_src=twsrc%5Etfw">September 30, 2024</a></blockquote>
<script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></div>
</figure>
Five years later, in 2009, Cuban praised Trump for his marketing nous. &#8220;Donald&#8217;s amazing. He sets the standard for marketing and promotion and to get him involved in MMA and to partner with him is an amazing opportunity for HDNet,&#8221; he said.
Why It Matters: Despite their rivalry, Cuban initially supported Trump&#8217;s political aspirations but later became a vocal critic due to their differing views on success and the Republican nominee&#8217;s incessant self-promotion.
The duo also collaborated in 2009 to promote a mixed martial arts (MMA) event through Cuban&#8217;s HDNet network.
In 2017, Trump also retaliated against Cuban, saying the billionaire wasn&#8217;t smart enough to run for president.
<figure class="wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter"> 
<div class="wp-block-embed__wrapper">
<blockquote class="twitter-tweet" data-width="500" data-dnt="true">I know Mark Cuban well. He backed me big-time but I wasn&#39;t interested in taking all of his calls.He&#39;s not smart enough to run for president!
&mdash; Donald J. Trump (@realDonaldTrump) <a href="https://twitter.com/realDonaldTrump/status/830769247185952772?ref_src=twsrc%5Etfw">February 12, 2017</a></blockquote>
<script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></div>
</figure>
Last week, Cuban <a href="https://www.benzinga.com/news/24/09/41078897/billionaire-mark-cuban-admits-to-being-a-trump-supporter-in-2016-credits-long-conversation-with-form">admitted to supporting</a> Trump in 2016 but said that a conversation with his running mate JD Vance led to a change of heart.
Earlier this month, the <a href="https://www.benzinga.com/news/24/09/40849505/mark-cuban-says-he-truly-does-not-hate-trump-but-calls-him-a-lousy-president-if-he-wasnt-running">billionaire also said</a>, &#8220;I truly don't hate him [Trump] at all. I just think he was&nbsp;and would be a lousy&nbsp;president.&#8221;
In August while speaking with Vivek Ramaswamy, Cuban said, &#8220;I actually started off supporting Donald and then I got to know him better. I was like, ‘He's great, he's not a typical Stepford candidate.' I thought that was a positive, and then I got to know him.&#8221;
He added, &#8220;He was unethical then, and he&#8217;s still unethical.&#8221;
Cuban has been <a href="https://www.benzinga.com/markets/cryptocurrency/24/09/41032465/mark-cuban-is-one-of-kamala-harris-most-effective-surrogates-says-former-sc-house-rep-baka">openly supporting</a> Vice President Kamala Harris, the Democratic candidate for the 2024 presidential election.
Read Next:
<ul>
<li><a href="https://www.benzinga.com/news/24/09/41083520/larry-hogan-says-trump-questioning-kamala-harris-intelligence-outrageous-and-unacceptable-he-is-his?itm_source=parsely-api" target="_blank" rel="noreferrer noopener">Larry Hogan Says Trump Questioning Kamala Harris&#8217; Intelligence &#8216;Outrageous And Unacceptable&#8217;: He Is His Own &#8216;Worst Enemy&#8217;</a></li>
</ul>
Disclaimer: This content was partially produced with the help of AI tools and was reviewed and published by Benzinga editors.
Photos courtesy: Shutterstock

Politics

Media

Mark Cuban Once Supported Trump's Political Aspirations And Called Him 'Amazing,' But The Former TV Rivals Have Shared A Love-Hate Relationship: The 'Shark Tank' Star Made This Promise To Himself After Leaving Ex-President's Office In 2004

Li Auto Inc. ("Li Auto" or the "Company") (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/LI#NASDAQ">LI</a>, HKEX: 2015)))), a leader in China's new energy vehicle market, today announced that it delivered&nbsp;53,709 vehicles in September 2024, up 48.9% year over year. This brought the Company's third-quarter deliveries to 152,831, increasing by 45.4% year over year. As of September 30, 2024, Li Auto had delivered a total of&nbsp;341,812 vehicles in 2024, with cumulative deliveries reaching 975,176. &nbsp;

Reported Earlier, Li Auto Delivered 53,709 Vehicles In September, Up By 48.9% YoY

ZEEKR Intelligent Technology Holding Limited ("ZEEKR" or the "Company") (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/ZK#NYSE">ZK</a>), a global premium electric mobility technology company, today announced its delivery results for September 2024.
ZEEKR delivered 21,333 vehicles in September 2024, a 77% year-over-year increase. Year-to-date,&nbsp;ZEEKR has delivered 142,873 vehicles in 2024, representing 81% growth over the same period last year. As of the end of September 2024,&nbsp;ZEEKR's cumulative deliveries reached 339,506.
On September 20, 2024, ZEEKR&nbsp;officially&nbsp;unveiled its premium electric five-seater SUV, the ZEEKR 7X, with deliveries commencing the very next day. The ZEEKR 7X is designed to challenge the conventional, seamlessly combining luxurious comfort with robust off-road capabilities, making it ideal for both urban and challenging conditions.&nbsp;

Reported Earlier, Zeekr Delivered 21,333 Vehicles In September, Up By 77% YoY

Greenfire Resources Ltd. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/GFR#NYSE">GFR</a>) (TSX:<a class="ticker" href="https://www.benzinga.com/stock/GFR#TSX">GFR</a>) ("Greenfire" or the "Company"), a Calgary-based energy company focused on the production and development of thermal energy resources from the Athabasca region of Alberta, Canada announces that the Alberta Securities Commission ("ASC") has set November 5, 2024 as the date for the hearing in respect of the application made by certain limited partnerships managed by Waterous Energy Fund Management Corp. (collectively, "WEF") and parties that it has entered into share purchase agreements with, namely Allard Services Limited ("Allard"), a corporation controlled by former director and Greenfire Board Chair Julian McIntyre, and Annapurna Limited ("Annapurna"), a corporation controlled by former Greenfire director Venkat Siva, and Modro Holdings LLC (together with Allard and Annapurna, the "Selling Shareholders") requesting that the ASC, among other things, cease trade the Company's shareholder protection rights plan agreement (the "Rights Plan").
Greenfire adopted the Rights Plan following the announcement on September 16, 2024 that WEF had entered into agreements with each of the Selling Shareholders to acquire 43.3% of the issued and outstanding common shares of the Company. The Company intends to defend the necessity of its Rights Plan at the ASC hearing to ensure, to the extent possible, that all shareholders of Greenfire are treated fairly and equally in connection with any unsolicited take-over bid or other attempt to acquire control of Greenfire, and to provide the Board sufficient opportunity to identify, develop and negotiate potential value-enhancing alternatives, if available, that would benefit all shareholders of the Company.
Greenfire also announces that today each of Julian McIntyre, the principal of Selling Shareholder Allard, and Venkat Siva, the principal of Selling Shareholder Annapurna, has tendered their resignation as a director of the Company.

TSX:GFR

Reported Earlier, Greenfire Faces Key Alberta Securities Commission Hearing Over Shareholder Rights Plan Amid Takeover Bid, Former Directors Resign

NASDAQ-listed <a href="https://pr.report/35db">AGAPE ATP Corporation ("ATPC")</a>, is proud to announce a strategic collaboration with <a href="https://pr.report/35dc">FORMEDIC Technologies Sdn. Bhd. ("FORMEDIC Technologies")</a> to introduce <a href="https://pr.report/35dd">LEGA</a>, an electronic chest percussion device for respiratory care. This partnership marks a major advancement in respiratory health, as the two companies combine their strengths to address the growing demand for advanced respiratory solutions.
LEGA, FORMEDIC's flagship product, assists patients with chronic obstructive pulmonary diseases ("COPD"), pneumonia, bronchiectasis, and other lung-related conditions by providing critical support for airway clearance and secretion management. LEGA helps to manage secretion drainage and airway clearance, offering much-needed relief to patients both adults and children, facing respiratory difficulties in both hospital and home care settings. This device has already gained significant traction in the medical field, with close to 2,000 units used in major hospitals and rehabilitation centres in Malaysia and globally.
For ATPC, this collaboration brings opportunities in the <a href="https://pr.report/35de">fast-growing respiratory care market, estimated to reach USD 25.95 billion in 2024, with a strong growth trajectory, estimating it to hit USD 49.84 billion by 2031</a>1. As respiratory diseases continue to rise globally, this partnership positions ATPC to capitalise on the increasing demand for advanced respiratory solutions, as well as diversifying its wellness portfolio with a proven medical device.

ATPC

Reported Earlier, AGAPE ATP and FORMEDIC Partner to Launch Advanced Respiratory Device LEGA for COPD and Lung Care

Shigeru Ishiba has been elected as Japan&#8217;s new prime minister, replacing Fumio Kishida and raising questions about future U.S.-Japan relations. 
What Happened: Experts predict how Shigeru&#8217;s appointment might crop up changes in the relations between Tokyo and Washington, as <a href="https://www.politico.com/news/magazine/2024/09/29/japans-prime-minister-ishiba-00181546">reported </a>by Politico on Monday. According to Jesper Koll, a German-born economist in Tokyo, Ishiba must overcome his reputation for micromanagement and stubbornness. Ishiba lacks a grand vision, Koll added.
For Washington, Ishiba&#8217;s stance on military relations is crucial. He has suggested revising the U.S. forces deployment agreement and amending Japan&#8217;s pacifist constitution. Ishiba also proposed an Asian NATO, potentially elevating Japan to a peer ally of the U.S.
Gerry Curtis, a retired Columbia scholar, noted that Ishiba views the current U.S. deal as outdated.
"He could be a problem for the U.S.," he said.
Ken Weinstein, a prominent Japan watcher, described Ishiba as the "hardest for Americans to read&#8221; among the other candidates.
A Japanese official explained that 60% of Ishiba&#8217;s motivation is to enhance deterrence and strengthen the alliance, while 40% is about restoring Japanese sovereignty. This dual motive makes Washington uneasy.
Ishiba stated that security issues would be discussed with the next U.S. president post-November elections. Additionally, Japan faces challenges from U.S. protectionist trade policies and restrictions on technology transfers to China, impacting Japanese manufacturers.
Hiro Akita of Nikkei described Ishiba as a realist who understands Japan must adapt to a changing world. While not seeking to push America back, Ishiba&#8217;s leadership could still stir the waters of U.S.-Japan relations.
See Also: <a href="https://www.benzinga.com/general/politics/24/09/41079936/shaq-called-trump-a-straight-up-guy-before-presidency-i-think-he-just-says-it-wrong-but-did-the-?itm_source=parsely-api" target="_blank" rel="noreferrer noopener">Shaq Called Trump &#8216;A Straight-Up Guy&#8217; Before Presidency, &#8216;I Think He Just Says It Wrong&#8217; – But Did The NBA Legend Actually Vote For Trump In 2016?</a>
Despite his reputation for micromanagement, Ishiba&#8217;s election marks a shift from the policies of former Prime Minister Shinzo Abe. His pragmatic stance could bring changes to Japan&#8217;s domestic and international policies.
Why It Matters: The election of Shigeru Ishiba has already had significant economic repercussions. On Monday, Japan&#8217;s key stock market gauge<a href="https://www.benzinga.com/markets/asia/24/09/41084907/japans-nikkei-plummets-over-2-000-points-amid-change-of-guard-while-chinese-market-extends-stimulus">, the Nikkei 225</a>, plummeted over 2,000 points, or 5.02%, amid the change of leadership. The index, heavily reliant on exports, reacted negatively to Ishiba&#8217;s victory, reflecting investor uncertainty about his policies. 
Additionally, Ishiba&#8217;s stance on international trade and defense could <a href="https://www.benzinga.com/news/24/09/40745941/japan-pm-candidate-warns-bidens-opposition-to-nippons-us-steel-acquisition-could-undermine-the-trust">strain Japan&#8217;s relationship</a> with the United States. Earlier this month, Ishiba warned that President Joe Biden&#8216;s opposition to Nippon Steel&#8216;s acquisition of U.S. Steel might undermine trust between the allies. 
Did You Know?
<ul>
<li>Congress Is Making Huge Investments.&nbsp;<a href="https://www.benzinga.com/gov-trades" target="_blank" rel="noreferrer noopener">Get Tips On What They Bought And Sold Ahead Of The 2024 Election With Our Easy-to-Use Tool</a></li>
</ul>
Image by Sakaori via Wikimedia Commons
This story was generated using <a href="https://www.benzinga.com/author/benzinga-neuro">Benzinga Neuro</a> and edited by <a href="https://www.benzinga.com/topic/Pooja-Rajkumari" target="_blank" rel="noreferrer noopener">Pooja Rajkumari</a>

Global

General

Japan's Shigeru Ishiba 'Could Be A Problem' For US, Experts Warn: 'Hardest For Americans To Read'

CPI Card Group Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PMTS#NASDAQ">PMTS</a>) ("CPI" or the "Company"), a payments technology company and leading provider of credit, debit and prepaid card and digital solutions, including Software-as-a-Service (SaaS) based instant issuance, today announced the pricing of a registered underwritten secondary public offering of 1,200,000 shares of the Company's common stock to be sold by certain stockholders affiliated with Parallel49 Equity (the "selling stockholders"), at a public offering price of $21.00 per share. The underwriters were also granted a 30-day option to purchase up to an additional 180,000 shares of common stock from the selling stockholders at the public offering price, less the underwriting discount. The offering is expected to close on or about October 2, 2024, subject to the satisfaction of customary closing conditions.
The Company is not offering any shares of common stock in the offering and will not receive any proceeds from the sale of common stock by the selling stockholders. Total gross proceeds from the offering to the selling stockholders, before deducting the underwriting discount and other estimated offering expenses, are expected to be approximately $25.2 million.

Offerings

PMTS

CPI Card Group Selling Stockholders Priced $25.2M Secondary Public Offering of 1.2M Shares At $21/Share

WISeKey International Holding Ltd. ("WISeKey") ((SIX: WIHN, NASDAQ:<a href="https://www.benzinga.com/stock/WKEY#NASDAQ">WKEY</a>), a leader in cybersecurity, AI, Blockchain, and IoT operating as a holding company, today announced that will be initiating a awareness campaign to promote a major semiconductor fabrication facility (fab) project in Switzerland which marks a crucial step in the country's journey toward self-reliance in chip production and positions Switzerland as an emerging hub in the semiconductor industry.
For many years, WISeKey has been at the forefront of such efforts and has built an extensive expertise in semiconductors. Via its subsidiary. SEALSQ Corp (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/LAES#NASDAQ">LAES</a>), which focuses on semiconductors, PKI, and post-quantum technology products, WISeKey offers countries the opportunity to develop their own semiconductor personalization centers through Public-Private Partnerships (PPPs). This initiative aims to reduce reliance on foreign semiconductor manufacturing, thereby enhancing global supply chain security.
The development of a ab in Switzerland will require a careful balance of incentives, support, R&amp;D, innovation, and access to capital. As highly advanced facilities, semiconductor fabs face escalating costs due to various factors, and each project presents unique requirements and cost considerations. WISeKey aims to raise awareness of the essential role a Swiss-based fab will play in building the foundations for the country's innovation landscape. Given the project's complexity and cost, establishing a close partnership and a solid investment case is crucial to its success.
The project's objective in Switzerland is to start with a mini fab (a smaller-scale semiconductor fabrication facility) and gradually expand it into a full-scale semiconductor fab over the next 10 years. This phased approach allows for manageable investment, initial production capabilities, and flexibility to scale operations in line with technological advancements and market demands. Starting with a mini fab can cost between $100 million to $1.5 billion, depending on the desired technology node and production capacity. Over time, the facility can be expanded with the latest equipment and processes, eventually reaching the scale and capability of a full fab, which may involve a total investment of several billion. This gradual growth strategy aligns with Switzerland's goal of fostering a domestic semiconductor ecosystem and innovation cluster.
Currently, Switzerland heavily relies on imports to meet its semiconductor needs. This new fab project is set to mitigate that dependence, enhance the domestic chip production ecosystem, create new jobs, and attract further investments in the technology and space sector. Locally produced chips will become essential for various industries within Switzerland, contributing to a more resilient global supply chain.

LAES

WKEY

WISeKey and SEALSQ Push for Switzerland's First Semiconductor Fab to Boost Domestic Chip Production

XPeng Inc. (("XPENG" or the "Company, NYSE:<a href="https://www.benzinga.com/stock/XPEV#NYSE">XPEV</a>), a leading Chinese smart electric vehicle ("Smart EV") company, today announced its vehicle delivery results for September and the third quarter 2024.
In September 2024, XPENG delivered 21,352 Smart EVs, a new record for monthly deliveries, representing increases of 39% year-over-year and 52% over the prior month. At the same time, the first month of deliveries of XPENG MONA M03 exceeded 10,000 units. For the first nine months of 2024, XPENG delivered 98,561 Smart EVs, a 21% increase from the same period last year.
With a broad array of superior configurations and competitive pricing, XPENG MONA M03 has experienced a significant increase in orders since its market launch. XPENG and supply chain partners are sparing no effort to prepare for XPENG MONA M03's further production ramp-up.
In September, XNGP's monthly active user penetration rate in urban driving reached 83%. XPENG rolled out its AI Tianji XOS 5.3 to all eligible owners in China on September 25, enhancing their experience with 32 feature updates and 38 functional upgrades. Empowered by end-to-end large AI models, XPENG's ADAS features can deliver seamless smart driving on all public roads, including passing electronic toll collection (ETC), navigating U-turns and roundabouts, and much more.
Additionally, after successful launch events in Madrid and Lisbon in September, XPENG officially introduced the G9, G6 and P7 models to the Spanish and Portuguese markets.
Looking ahead, the Company expects to unveil XPENG P7+, positioned as AI-defined car, in October 2024. XPENG will also showcase its state-of-the-art AI technologies and applications and its new model lineup at the 2024 Paris Motor Show from October 14 to 21.

XPEV

XPeng Reported Delivery Of 21,352 Smart EVs In September 2024, Up By 39% YoY And 52% MoM

<a href="https://c212.net/c/link/?t=0&amp;l=en&amp;o=4267071-1&amp;h=2471754948&amp;u=http%3A%2F%2Fwww.group1corp.com%2F&amp;a=Group+1+Automotive%2C+Inc">Group 1 Automotive, Inc</a>. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/GPI#NYSE">GPI</a>) ("Group 1" or the "Company"), a Fortune 250 automotive retailer with 260 dealerships located in the U.S. and U.K.,&nbsp;announced the appointment of Mark Raban as Chief Executive Officer ("CEO") of Group 1 Automotive U.K.
Raban brings more than 20 years of executive experience in automotive retail operations and finance to Group 1.&nbsp; In this new role, he will oversee the integration of the recently acquired Inchcape dealerships to drive strategic growth in the U.K.&nbsp; Leveraging the Company's expanded brand portfolio and presence, Raban will also focus on enhancing customer experience and reinforcing Group 1's strong OEM partnerships.
"Mark is a proven leader with a history of success in the U.K. motor trade," said Daryl Kenningham, Group 1's President and CEO.&nbsp; "Following the transformative growth of our U.K. business, he will be instrumental in creating a high-performing culture among our team members and engaging customers across our expanded dealership network."
Prior to joining Group 1, Raban progressed from Chief Financial Officer ("CFO") to CEO at Lookers Motor Group, a dealership group in the U.K. and Ireland.&nbsp; Prior to joining Lookers, he served as CFO of Marshall Motor Holdings and held senior finance roles at companies such as Inchcape Retail, Selfridges, and Borders.

Management

Group 1 Automotive Tapped Mark Raban Of Lookers Motor Group as CEO of UK Operations

Daiichi Sankyo (TSE: 4568) and AstraZeneca's (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AZN#NASDAQ">AZN</a>) supplemental Biologics License Application (sBLA) for ENHERTU&#xAE; (fam-trastuzumab deruxtecan-nxki) has been accepted and granted Priority Review in the U.S. for the treatment of adult patients with unresectable or metastatic HER2 low (IHC 1+ or IHC 2+/ISH-) or HER2 ultralow (IHC 0 with membrane staining) breast cancer who have received at least one endocrine therapy in the metastatic setting.
ENHERTU is a specifically engineered HER2 directed DXd antibody drug conjugate (ADC) discovered by Daiichi Sankyo and being jointly developed and commercialized by Daiichi Sankyo and AstraZeneca.
The U.S. Food and Drug Administration (FDA) grants Priority Review to applications for medicines that, if approved, would offer significant improvements over available treatment options by demonstrating safety or efficacy improvements, preventing serious conditions or enhancing patient compliance. The Prescription Drug User Fee Act (PDUFA) date, the FDA action date for their regulatory decision, is February 1, 2025. The Priority Review follows receipt of Breakthrough Therapy Designation <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.daiichisankyo.com%2Ffiles%2Fnews%2Fpressrelease%2Fpdf%2F202408%2F20240819_E1.pdf&amp;esheet=54129231&amp;newsitemid=20240930807595&amp;lan=en-US&amp;anchor=granted&amp;index=1&amp;md5=c82129aaf52e5fdfcdcfd5c5d0f72567">granted</a> by the FDA for ENHERTU based on data from the <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fclinicaltrials.gov%2Fstudy%2FNCT04494425&amp;esheet=54129231&amp;newsitemid=20240930807595&amp;lan=en-US&amp;anchor=DESTINY-Breast06&amp;index=2&amp;md5=ecfc5698cd40f1242f214ba893845e59">DESTINY-Breast06</a> phase 3 trial in August 2024.
Hormone receptor (HR) positive, HER2 negative is the most common breast cancer subtype, accounting for approximately 70% of all breast cancers.1 Despite being classified as HER2 negative, many of these tumors still carry some level of HER2 expression.2 It is estimated that up to 85% to 90% of tumors historically classified as HR positive, HER2 negative, may be HER2 low or HER2 ultralow.3,4
The sBLA is based on data from DESTINY-Breast06 <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.daiichisankyo.com%2Ffiles%2Fnews%2Fpressrelease%2Fpdf%2F202406%2F20240602_E2.pdf&amp;esheet=54129231&amp;newsitemid=20240930807595&amp;lan=en-US&amp;anchor=presented&amp;index=3&amp;md5=60d743b75d92125e38563f950191d661">presented</a> as a late-breaking oral session at the 2024 American Society of Clinical Oncology (#ASCO24) Annual Meeting and recently published in <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.nejm.org&amp;esheet=54129231&amp;newsitemid=20240930807595&amp;lan=en-US&amp;anchor=The+New+England+Journal+of+Medicine&amp;index=4&amp;md5=1e3a45484df713407df2ad6cdbca0eba">The New England Journal of Medicine</a>. In the overall trial population, ENHERTU reduced the risk of disease progression or death by 37% by blinded independent central review (BICR) versus chemotherapy (hazard ratio [HR] 0.63; 95% confidence interval [CI]: 0.53-0.75; p&lt;0.0001). Median progression-free survival (PFS) was 13.2 months with ENHERTU compared to 8.1 months with chemotherapy.
Results were consistent in patients with HER2 low expression and HER2 ultralow expression. In the primary endpoint analysis of patients with HR positive, HER2 low metastatic breast cancer, median PFS was 13.2 months in the ENHERTU arm compared to 8.1 months in the chemotherapy arm (HR 0.62; 95% CI: 0.51-0.74; p&lt;0.0001), as assessed by BICR. In a prespecified exploratory analysis of patients with HER2 ultralow expression, ENHERTU showed a median PFS of 13.2 months versus 8.3 months, respectively (HR 0.78; 95% CI: 0.50-1.21).
The safety profile of ENHERTU in DESTINY-Breast06 was consistent with previous breast cancer clinical trials with no new safety concerns identified. The most common grade 3 or higher treatment related treatment emergent adverse events (TEAEs) occurring in 5% or more of patients treated with ENHERTU were neutropenia (20.7%), leukopenia (6.9%) and anemia (5.8%). Interstitial lung disease (ILD) or pneumonitis occurred in 11.3% of patients treated with ENHERTU. The majority of ILD or pneumonitis events were low grade (grade 1 [n=7; 1.6%] or grade 2 [n=36; 8.3%]). There were three grade 3 ILD events (0.7%), zero grade 4 events and three grade 5 events (0.7%) as determined by an independent adjudication committee.
"This Priority Review highlights the potential to expand the existing indication of ENHERTU in HER2 low metastatic breast cancer to include use in an earlier disease setting as well as in a broader patient population that includes HER2 ultralow," said Ken Takeshita, MD, Global Head, R&amp;D, Daiichi Sankyo. "We look forward to working closely with the FDA with the goal of bringing ENHERTU to more patients as quickly as possible."
"While endocrine therapies are widely used in the initial treatment of HR positive metastatic breast cancer, most patients see limited benefit with additional lines of treatment and subsequent chemotherapy is associated with poor response rates and outcomes," said Susan Galbraith, MBBChir, PhD, Executive Vice President, Oncology R&amp;D, AstraZeneca. "The results from DESTINY-Breast06 show that ENHERTU has the potential to evolve the current HR positive treatment landscape and become the first targeted treatment for patients with HER2 low or HER2 ultralow expression following endocrine therapy."

FDA Grants Priority Review for Daiichi Sankyo and AstraZeneca's ENHERTU in Breast Cancer Treatment

With U.S. stock futures trading lower this morning on Tuesday, some of the stocks that may grab investor focus today are as follows:
<ul>
<li>Wall Street expects Acuity Brands, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/AYI#NYSE">AYI</a>) to report quarterly earnings at $4.28 per share on revenue of $1.02 billion before the opening bell, according to data from <a href="https://pro.benzinga.com/dashboard">Benzinga Pro</a>. Acuity Brands shares gained 1.7% to $279.94 in after-hours trading.</li>
<li>ReposiTrak, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/TRAK#NYSE">TRAK</a>) reported better-than-expected fourth-quarter financial results and increased its quarterly dividend by 10%. ReposiTrak shares gained 4.6% to $19.32 in the after-hours trading session.</li>
<li>Analysts expect McCormick &amp; Company, Incorporated (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/MKC#NYSE">MKC</a>) to post earnings at 67 cents per share on revenue of $1.67 million for the latest quarter. The company will release earnings before the markets open. McCormick shares gained 0.4% to $82.60 in the after-hours trading session.</li>
</ul>
Check out our <a href="https://www.benzinga.com/premarket/">premarket coverage here</a>
<ul>
<li>Biohaven Ltd. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BHVN#NYSE">BHVN</a>) reported a proposed $250 million public offering of common shares. Biohaven shares fell 1.9% to $49.00 in the after-hours trading session.</li>
<li>Analysts expect NIKE, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/NKE#NYSE">NKE</a>) to post quarterly earnings at 52 cents per share on revenue of $11.65 million after the closing bell. Nike shares fell 0.1% to $88.31 in after-hours trading.</li>
</ul>
Check This Out:
<ul>
<li><a href="https://www.benzinga.com/markets/24/09/41102060/jim-cramer-hand-picks-these-3-stocks-to-ride-the-crest-of-the-chinese-stimulus-frenzy">Jim Cramer Hand Picks These 3 Stocks To Ride The Crest Of The Chinese Stimulus Frenzy</a></li>
</ul>
Photo courtesy: Shutterstock

Earnings

Long Ideas

Pre-Market Outlook

Markets

Trading Ideas

BHVN

TRAK

Acuity Brands, Nike And 3 Stocks To Watch Heading Into Tuesday

<a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fnextracker.com%2F&amp;esheet=54129605&amp;newsitemid=20240930556809&amp;lan=en-US&amp;anchor=%3Cstrong%3ENextracker+%28Nasdaq%3A+NXT%29%2C%3C%2Fstrong%3E&amp;index=1&amp;md5=df3d8ea60b226fe827440498fc5ff3c3">Nextracker (NASDAQ:</a><a href="https://www.benzinga.com/stock/NXT#NASDAQ">NXT</a>),a leading global provider of intelligent solar trackers, foundations, and software solutions, today inaugurated India's first Center for Solar Excellence (CFSE) in Hyderabad, India. Spanning across 13 acres this state-of-the-art facility will serve to advance solar tracker technology, further accelerating the region's energy transition.
The CFSE will feature a 30,000 square foot, state-of-the-art lab, a comprehensive solar tracker installation, and training facilities encompassing the entire project lifecycle—from structural, mechanical, and electrical design to construction, operation, and maintenance. Working closely with supply chain partners, customers, and third-party laboratories, Nextracker's cross-functional team of experts will be developing, testing, and commercializing proprietary technologies.&nbsp;

Nextracker To Open India's First Solar Excellence Center to Boost Renewable Energy Innovation

Nobel laureate Paul Krugman has taken a potshot at former President Donald Trump&#8216;s campaign for focusing on what he <a href="https://www.benzinga.com/markets/equities/24/09/40743901/elon-musk-and-trumps-federal-efficiency-plans-slammed-by-paul-krugman-economist-warns-about-risk">describes as &#8220;imaginary&#8221; problems</a>.
What Happened: In a post on X, formerly Twitter, Krugman accused the Trump campaign of denouncing a non-existent bad economy, runaway crime, and alleged failures by President Joe Biden and Vice President Kamala Harris&#8216; administration.
According to Krugman, &#8220;We've all become desensitized, but it's amazing how at this point the Trump campaign rests entirely on denouncing things that aren't happening — a imaginary bad economy, imaginary runaway crime and now an imaginary failure of Biden and Harris to respond to natural disaster<a href="https://x.com/paulkrugman/status/1840868481807298587"></a>.&#8221; 
He elaborated on his views in an opinion <a href="https://www.nytimes.com/2024/09/30/opinion/trump-inflation.html">piece</a> for The New York Times published the same day.
In his opinion piece titled &#8220;Why Trumponomics Could Lead to Trumpflation,&#8221; Krugman warned that Trump&#8217;s economic policies could lead to significant inflation. He argued that Trump&#8217;s proposed high tariffs, mass deportations, and undermining of the Federal Reserve&#8217;s independence would disrupt the economy.
Krugman also highlighted that the Federal Reserve&#8217;s preferred measure of consumer prices rose only 2.2% over the past year, close to its 2% target, without causing a recession. 
He credited the Biden administration for not pressuring the Fed to keep rates low, which helped manage inflation expectations.
Krugman concluded that Trump&#8217;s policies could lead to long-term stagflation, contrasting the current administration&#8217;s handling of economic issues.
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<blockquote class="twitter-tweet" data-width="500" data-dnt="true">We've all become desensitized, but it's amazing how at this point the Trump campaign rests entirely on denouncing things that aren't happening — a imaginary bad economy, imaginary runaway crime and now an imaginary failure of Biden and Harris to respond to natural disaster
&mdash; Paul Krugman (@paulkrugman) <a href="https://twitter.com/paulkrugman/status/1840868481807298587?ref_src=twsrc%5Etfw">September 30, 2024</a></blockquote>
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See Also: <a href="https://www.benzinga.com/markets/equities/24/09/41084225/economist-ben-golub-sounds-alarm-on-upcoming-us-shipping-strike-affecting-36-ports-chaotic-suppl?itm_source=parsely-api" target="_blank" rel="noreferrer noopener">Economist Ben Golub Sounds Alarm On Upcoming US Shipping Strike Affecting 36 Ports</a>
Why It Matters: Krugman&#8217;s comments come amid heightened scrutiny of Trump&#8217;s economic policies. Earlier this month, Krugman criticized Elon Musk and Trump&#8217;s federal efficiency plans, warning about risks to Medicare and Social Security. 
He stated, &#8220;The federal government is an <a href="https://www.benzinga.com/markets/equities/24/09/40743901/elon-musk-and-trumps-federal-efficiency-plans-slammed-by-paul-krugman-economist-warns-about-risk">insurance company with an army</a>. You can&#8217;t make major spending cuts without slashing Social Security, Medicare and Medicaid and/or weakening national defense.&#8221;
In mid-September, Trump voiced his disapproval of the Federal Reserve&#8217;s <a href="https://www.benzinga.com/news/24/09/40931251/trump-isnt-happy-with-jerome-powells-50-bps-rate-cut-maneuver-i-guess-it-shows-the-economy-is-very-b">decision to cut its benchmark interest rate by half a percentage point</a>, suggesting it indicated a faltering U.S. economy or a politically motivated action. He said, &#8220;I guess it shows the economy is very bad to cut it by that much, assuming that they are not just playing politics.&#8221; 
Additionally, Trump has claimed that inflation has cost <a href="https://www.benzinga.com/personal-finance/24/09/41047735/trump-claims-inflation-has-cost-american-households-28-000-is-he-right-heres-what-financial-expe">American households $28,000</a>, a figure that has sparked debate among economists and analysts. During a rally in Las Vegas, Trump asserted that &#8220;the worst inflation in American history&#8221; has caused severe financial strain for American families.
Adding to the controversy, Trump recently launched a $100,000 luxury watch collection, while his wife, Melania Trump, voiced concerns over <a href="https://www.benzinga.com/news/24/09/41080258/while-trump-launches-100k-luxury-watch-wife-melania-trump-talks-about-rising-inflation-the-country-i">rising inflation and its impact on American families</a>. 
Read Next:
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<li><a href="https://www.benzinga.com/markets/equities/24/09/41087957/us-stocks-set-for-flattish-start-as-traders-eye-job-data-jerome-powell-speech-and-looming-dock-w?itm_source=parsely-api" target="_blank" rel="noreferrer noopener">Nasdaq, S&amp;P Futures Point To Nervy Start To The Week: What&#8217;s Going On</a></li>
</ul>
Image Via Flickr
This story was generated using <a href="https://www.benzinga.com/author/benzinga-neuro">Benzinga Neuro</a> and edited by <a href="https://www.benzinga.com/topic/Kaustubh-Bagalkote" target="_blank" rel="noreferrer noopener">Kaustubh Bagalkote</a>

Economics

Nobel Laureate Paul Krugman Slams Trump, Says Campaign 'Rests Entirely On Denouncing' Imaginary Things: Praises Biden-Harris Administration's Handling Of Inflation

Chrysler parent Stellantis NV (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/STLA#NYSE">STLA</a>) is recalling 154,032&nbsp;Jeep plug-in hybrid SUVs in the U.S. owing to fire risks, the company said in a statement on Monday. 
What Happened: The company is recalling nearly 154,000 vehicles in the U.S., 14,038 in Canada, 673 in Mexico, and about 25,502 outside North America, the company said, taking the total recall population around the globe to 194,245 units.
The company decided to recall the vehicles after a routine review of customer data unveiled 13 fire instances when the vehicles were parked and turned off. The recall population includes model year 2020-2024 of the Jeep Wrangler 4xe and 2022-2024 Jeep Grand Cherokee 4xe SUVs.
Instructions For Drivers: To reduce the risk of vehicle fire, the company advised owners not to recharge the vehicles but to park them away from structures or other vehicles until the remedy is deployed. The fix is &#8216;imminent,&#8217; the company added. 
Stellantis did not immediately respond to <a href="https://pro.benzinga.com/dashboard">Benzinga&#8217;s</a> request for comment on the cause of the fires.
Why It Matters: Stellantis also <a href="https://www.benzinga.com/markets/equities/24/09/41089577/whats-going-on-with-stellantis-stock-monday">lowered its financial guidance</a> for 2024 on Monday as it seeks to bring down inventory levels in the U.S. The company now expects an adjusted operating income margin of between 5.5 and 7% for FY 2024, down from its previous outlook of double-digit margins.
The company now also expects industrial free cash flow in the range of negative five billion euros and negative 10 billion euros versus the prior positive cash flow expectations.
The company is targeting dealer inventory of no more than 330,000 units by year-end 2024 in the U.S.
Price Action: Stellantis shares closed down 12.5% at $14.05 on Monday. The stock is down 39% year-to-date, according to data from <a href="https://pro.benzinga.com/dashboard">Benzinga Pro</a>. 
Check out more of Benzinga's Future Of Mobility coverage by&nbsp;<a href="https://www.benzinga.com/topic/mobility" target="_blank" rel="noreferrer noopener">following this link</a>.
Read More:
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<li><a href="https://www.benzinga.com/news/24/09/41060572/ev-sales-expected-to-gain-momentum-in-us-in-q3-even-as-market-leader-tesla-is-projected-to-decline-r" target="_blank" rel="noreferrer noopener">EV Sales Expected To Gain Momentum In US In Q3 Even As Market Leader Tesla Is Projected To Decline: Report</a></li>
</ul>
Photo courtesy: Stellantis

Tech

STLA

Stellantis Recalls Over 154K Jeep Plug-Hybrid SUVs In US Citing Fire Risk

Malaysia&#8217;s Prime Minister Anwar Ibrahim announced the introduction of a national cloud policy and artificial intelligence regulations on Tuesday, coinciding with significant investments by <a href="https://www.benzinga.com/news/24/04/38083584/can-china-us-tensions-propel-this-country-with-a-rich-semiconductor-heritage-as-the-next-chip-superp">global tech giants in the country</a>.
What Happened: The announcement coincides with a surge of investments by global tech giants in Malaysia over the past year, Reuters reported. These investments aim to build essential infrastructure to meet the rising demand for cloud and AI services.
Anwar stated that the national cloud policy will concentrate on four key areas: public service innovation, economic competitiveness, user trust and data security, and digital inclusivity.
The government will also establish a national AI office to coordinate initiatives, including a five-year technology action plan and a regulatory framework for ethical AI adoption within the next 12 months.
At a ground-breaking ceremony for Alphabet Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GOOG#NASDAQ">GOOG</a>) (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GOOGL#NASDAQ">GOOGL</a>) subsidiary Google&#8217;s new $2 billion data center, Anwar said, &#8220;We aim to position Malaysia as a hub for generative artificial intelligence and investments from tech partners will be critical in building a robust and secure digital infrastructure.&#8221;
Google announced that its investments in Malaysia would generate 26,500 jobs and add over $3 billion to the country&#8217;s GDP by 2030. 
Ruth Porat, Google&#8217;s President and Chief Investment Officer, stated, &#8220;Our investments are designed to provide high performing and reliability, meeting demand for cloud and AI services across the country.&#8221;&nbsp;
Digital investments have significantly boosted Malaysia&#8217;s economy this year, with growth surpassing market expectations in recent quarters. 
Google&#8217;s expansion is part of a broader move by tech companies into Southeast Asia, a region with a young, tech-savvy population of 670 million.
See Also: <a href="https://www.benzinga.com/news/24/09/41087287/elon-musk-responds-after-y-combinators-paul-graham-says-twitter-name-change-was-a-waste-of-time-you?itm_source=parsely-api" target="_blank" rel="noreferrer noopener">Elon Musk Responds After Y Combinator&#8217;s Paul Graham Says Twitter Name Change &#8216;Was A Waste Of Time:&#8217; &#8216;You Know Nothing&#8217;</a>
Why It Matters: Malaysia has been aggressively positioning itself as a key player in the global tech industry. 
In May, the country announced an ambitious plan to attract $107 billion in investments for its semiconductor sector, focusing on integrated circuit design, advanced packaging, and semiconductor chip manufacturing equipment.
This move aims to capitalize on <a href="https://www.benzinga.com/markets/asia/24/05/39044963/malaysia-targets-ambitious-107b-investment-to-boost-semiconductor-sector">Malaysia&#8217;s role in the semiconductor market</a>, contributing to 13% of global testing and packaging. Major firms like Intel Corp. and Infineon Technologies AG have already made substantial investments in the country.
In August, Amazon Web Services committed over $6 billion to establish a new cloud region in Malaysia, expected to contribute around $12.1 billion to the country&#8217;s GDP and support over 3,500 full-time jobs annually through 2038. This investment underscores the <a href="https://www.benzinga.com/markets/equities/24/08/40507491/amazon-web-services-commits-over-6b-to-malaysia-with-new-cloud-region">growing importance of Malaysia as a tech hub</a>.
Additionally, Micron Technology Inc. is considering <a href="https://www.benzinga.com/news/24/06/39404032/micron-technology-plans-major-us-expansion-and-eyes-malaysia-for-hbm-production-to-compete-with-sk-h">Malaysia for high-bandwidth memory chip production</a> to compete with South Korean rivals. This potential move is part of Micron&#8217;s strategy to capture a larger share of the AI-driven market.
Amid escalating <a href="https://www.benzinga.com/news/24/04/38083584/can-china-us-tensions-propel-this-country-with-a-rich-semiconductor-heritage-as-the-next-chip-superp">U.S.-China tech tensions</a>, Malaysia&#8217;s well-established infrastructure and skilled labor force have made it an attractive destination for global chip firms. The country&#8217;s expertise in the &#8220;back end&#8221; of semiconductor manufacturing, including assembly, testing, and packaging, has been a key factor in its growing importance.
Read Next: 
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<li><a href="https://www.benzinga.com/news/24/09/41078347/elon-musk-gets-labelled-as-an-outspoken-trump-supporter-after-journalist-gets-banned-on-x-for-publis?itm_source=parsely-api" target="_blank" rel="noreferrer noopener">Elon Musk Gets Labelled As An &#8216;Outspoken&#8217; Trump Supporter After Journalist Gets Banned On X For Publishing Leaked JD Vance Docs: &#8216;This Is Political&#8217;</a></li>
</ul>
Image Via Shutterstock 
This story was generated using <a href="https://www.benzinga.com/author/benzinga-neuro">Benzinga Neuro</a> and edited by <a href="https://www.benzinga.com/topic/Kaustubh-Bagalkote" target="_blank" rel="noreferrer noopener">Kaustubh Bagalkote</a>

GOOG

GOOGL

Malaysia Announces National Cloud Policy And AI Regulations As Google Breaks Ground On Its New $2B Data Center

Japanese investment firm Metaplanet Inc. has boosted its Bitcoin (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/btc/usd">BTC</a>) portfolio, purchasing an additional 107.91 BTCs valued at around $6.92 million.
What happened: The Tokyo Stock Exchange-listed firm disclosed its latest grab Tuesday, reaffirming its conviction in the world's largest cryptocurrency's potential.&nbsp;
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<blockquote class="twitter-tweet" data-width="500" data-dnt="true">&#x2A;Metaplanet purchases additional 107.91 <a href="https://twitter.com/search?q=%24BTC&amp;src=ctag&amp;ref_src=twsrc%5Etfw">$BTC</a>&#x2A; <a href="https://t.co/pPrRBGrJsC">pic.twitter.com/pPrRBGrJsC</a>
&mdash; Metaplanet Inc. (@Metaplanet_JP) <a href="https://twitter.com/Metaplanet_JP/status/1840954225796186287?ref_src=twsrc%5Etfw">October 1, 2024</a></blockquote>
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The stash was purchased at an average price of $64,189.55 per BTC. With the latest buy, Metaplanet raised its total Bitcoin holdings to 506.745, worth roughly $32.92 million. Shares of the company were up over 2% at last check. 
See Also: <a href="https://www.benzinga.com/markets/cryptocurrency/24/09/41102705/pay-taxes-with-bitcoin-ohio-senator-proposes-bill-for-crypto-tax-payments-but-theres-a-cat">Pay Taxes With Bitcoin? Ohio Senator Proposes Bill For Crypto Tax Payments, But There&#8217;s A Catch</a>
Why It Matters: Metaplanet has <a href="https://www.benzinga.com/markets/cryptocurrency/24/07/39658863/adopting-a-microstrategy-like-strategy-firm-listed-on-tokyo-stock-exchange-buys-2-5m-worth">made a concerted effort</a> to add the world&#8217;s largest digital asset to its portfolio to shield itself from Japan&#8217;s economic woes and the declining value of its national currency, the yen.
The sustained push has resulted in the company becoming Japan's biggest corporate holder of the leading cryptocurrency, <a href="https://bitcointreasuries.net/">according </a>to data from bitcointreasuries.net.
This firm followed in the footsteps of MicroStrategy, a U.S.-based software company that has led the charge in recent years to purchase Bitcoins as part of a corporate reserve strategy.
At the time of writing, MicroStrategy held 252,220 BTCs in its reserves, worth more than $16 billion, making it the biggest corporate holder of the cryptocurrency globally.&nbsp;
Price Action: At the time of writing, Bitcoin was exchanging hands at $63,698.50, down 1.19% in the last 24 hours, according to <a href="https://pro.benzinga.com/dashboard?_gl=1&#x2A;380nj0&#x2A;_ga&#x2A;MTEyOTAyOTcxMy4xNzEzMzY0NTYy&#x2A;_ga_V7ZK73W7N0&#x2A;MTcxNDk4MzIzMi42LjEuMTcxNDk4OTE0Ni4wLjAuMA..">data from Benzinga Pro</a>.
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<li><a href="https://www.benzinga.com/markets/cryptocurrency/24/09/41105426/if-you-invested-1-000-in-dogecoin-when-mark-cuban-and-the-dallas-mavericks-welcomed-the-me">If You Invested $1,000 In Dogecoin When Mark Cuban And The Dallas Mavericks Welcomed The Meme Crypto, Here&#8217;s How Much You&#8217;d Have Now</a></li>
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Photo courtesy: Shutterstock

Coverage of Bitcoin, Etherum, Ripple and all the latest digital currencies.

Cryptocurrency

$BTC

'Asia's MicroStrategy' Metaplanet Boosts Portfolio With Fresh Acquisition Of 107 Bitcoins Worth Nearly $7M

Chinese electric vehicle startups Li Auto Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/LI#NASDAQ">LI</a>) and XPeng Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/XPEV#NASDAQ">XPEV</a>) reported September deliveries, registering gains on both year-over-year and month-over-month basis. The report comes a day ahead of bigger rival Tesla Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TSLA#NASDAQ">TSLA</a>) is <a href="https://www.benzinga.com/analyst-ratings/analyst-color/24/09/41082647/tesla-could-report-slight-q3-deliveries-miss-amid-musks-political-controversies-mun">set to announce its global deliveries update</a>.
Li Auto: Beijing-based Li Auto said it sold 53,709 EVs in September and this marked a 48.9% increase from a year ago. On a month-over-month basis, sales climbed 11.61%.
Third-quarter deliveries totaled 152,831 units compared to the 145,000-155,000-unit the company guided to in late August.
&#8220;With the penetration rate of new energy vehicles surpassing 50%, the dominance of leading brands has become more pronounced. Since the beginning of the third quarter, the top three brands have captured over 50% of RMB200,000 and above NEV market,&#8221; Xiang Li, chairman and CEO, said in a statement.
Li Aiuto said order intake for Li L series and Li MEGA has seen a steady increase, leading to record deliveries in September. The company also expects to achieve the milestone of manufacturing and delivering its one-millionth vehicle in October.
See Also: <a href="https://www.benzinga.com/money/best-electric-vehicle-stocks">Best EV Stocks</a>
XPeng: XPeng delivered 21,352 EVs in September, a 39% year-over-year growth and a 52.12% month-over-month. The company said the first month deliveries of its XPeng Mona M03, an affordable electric sedan launched in late August, topped 10,000 units.
For the third quarter, the Guangzhou-based EV maker reported deliveries of 46,533 units, marking a 16% year-over-year increase. This exceeded the company&#8217;s guidance of 41,000 and 45,000 units.
XPeng said following the successful launch events in Madrid and Lisbon in September, XPENG officially introduced the G9, G6, and P7 models to the Spanish and Portuguese markets.
Looking ahead, the company expects to unveil XPENG P7+, positioned as an AI-defined car, in October. 
XPeng said it&nbsp;will showcase its state-of-the-art AI technologies and applications and its new model lineup at the 2024 Paris Motor Show from&nbsp;October 14 to 21.
Why It&#8217;s Important: The Chinese EV market has seen intensifying rivalry, with companies undercutting competition and also rolling out new models to cater to different segments of the market. To make matters worse, weakening economic fundamentals hurt demand. 
All this could be a thing of the past as China has shown intent to revitalize the domestic economy by <a href="https://www.benzinga.com/markets/asia/24/09/41003814/chinese-stocks-jump-as-central-bank-unveils-major-stimulus-to-spur-economy-a-step-in-the-right-direc">pouring in copious stimuli</a>.
Li Auto&#8217;s U.S.-listed ADRs closed Monday&#8217;s session down 0.50% at $25.65, according to <a href="https://benzinga.grsm.io/register174">Benzinga Pro data.</a> Xpeng ADRs closed down 4.25% at $12.18.
Check out more of Benzinga&#8217;s Future Of Mobility coverage by&nbsp;<a href="http://www.benzinga.com/topic/mobility" target="_blank" rel="noreferrer noopener">following this link</a>.
Read Next:
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<li><a href="https://www.benzinga.com/markets/equities/24/09/41082193/teslas-chinese-rival-nio-snags-1-9b-investment-from-parent-strategic-investors-as-it-forays-into">Tesla&#8217;s Chinese Rival Nio Snags $1.9B Investment From Parent, Strategic Investors As It Forays Into Mass Market</a></li>
</ul>
Photo courtesy: Shutterstock

Equities

TSLA

Tesla Rivals Li Auto, XPeng Clock Record September Deliveries, End Q3 On A Strong Note

A man in Ellis County, Texas, purchased a Taylor Swift-inspired guitar for $4,000 at an auction, <a href="https://www.benzinga.com/general/politics/24/09/40906814/hillary-clinton-condemns-elon-musks-rotten-and-creepy-post-about-taylor-swift-says-it-hints-at-s">only to smash it with a hammer</a>.
What Happened: In a video <a href="https://www.tmz.com/2024/09/30/taylor-swift-autographed-guitar-auction-destroys-smashes/">shared</a> by TMZ, the man, who has white hair, is seen repeatedly hitting the guitar with a hammer while the crowd cheers. He appeared ready to smash it on the ground before the auction&#8217;s host intervened.
The incident occurred at the annual Ellis County WildGame Dinner, a non-profit event aimed at raising funds for youth agricultural education in Ellis County, according to the organization's website. Swift has not yet commented on the video. 
Swift is currently preparing for the final dates of her record-breaking Eras Tour, which concludes on Nov. 3 in Indianapolis and has additional dates in Vancouver from Dec. 6-8. 
Recently, Swift endorsed Democratic presidential candidate and current Vice President Kamala Harris, who praised Swift for her courage and artistic achievements.
See Also: <a href="https://www.benzinga.com/news/24/09/41083520/larry-hogan-says-trump-questioning-kamala-harris-intelligence-outrageous-and-unacceptable-he-is-his?itm_source=parsely-api" target="_blank" rel="noreferrer noopener">Larry Hogan Says Trump Questioning Kamala Harris&#8217; Intelligence &#8216;Outrageous And Unacceptable&#8217;: He Is His Own &#8216;Worst Enemy&#8217;</a>
Why It Matters: Swift's Eras Tour has significantly impacted various sectors, including a 25% surge in demand for United Airlines Holdings Inc. flights, as fans <a href="https://www.benzinga.com/general/entertainment/24/09/40975413/we-watch-where-taylor-goes-because-our-demand-booms-taylor-swifts-eras-tour-sparks-25-fligh">travel to attend her concerts</a>. This highlights her influence on the economy and travel industry.
Additionally, Swift&#8217;s endorsement of Harris has stirred political discourse, drawing reactions from notable figures like Elon Musk and Hillary Clinton. Musk&#8217;s controversial post about Swift&#8217;s endorsement led to Clinton <a href="https://www.benzinga.com/general/politics/24/09/40906814/hillary-clinton-condemns-elon-musks-rotten-and-creepy-post-about-taylor-swift-says-it-hints-at-s">condemning his remarks</a>, calling them &#8220;rotten and creepy.&#8221;
Moreover, Mark Zuckerberg recently shared his parenting philosophy, advising his daughter to <a href="https://www.benzinga.com/news/24/09/40969914/zuckerberg-tells-his-daughter-she-cant-be-like-taylor-swift-you-cant-do-it-thats-not-available-to-yo">aspire to be herself rather than a celebrity like Swift</a>. This conversation underscores the cultural impact Swift has on younger generations and the broader societal discussions about fame and individuality.
Read Next: 
<ul>
<li><a href="https://www.benzinga.com/news/24/09/41084112/mark-zuckerberg-says-orion-is-probably-going-to-be-the-next-major-platform-after-phones-metas-new-ar?itm_source=parsely-api" target="_blank" rel="noreferrer noopener">Mark Zuckerberg Says, Orion &#8216;Is Probably Going To Be The Next Major Platform After Phones&#8217; — Meta&#8217;s New AR Wearables Real-Life Tony Stark Glasses In The Making?</a></li>
</ul>
Image Via Shutterstock 
This story was generated using <a href="https://www.benzinga.com/author/benzinga-neuro">Benzinga Neuro</a> and edited by <a href="https://www.benzinga.com/topic/Kaustubh-Bagalkote" target="_blank" rel="noreferrer noopener">Kaustubh Bagalkote</a>

Entertainment

Texas Man Spends $4K Buying Taylor Swift Guitar And Then Smashes It With A Hammer To Cheering Crowd

JMP Securities analyst Reni Benjamin reiterated a Buy rating on Prelude Therapeutics (PRLD – Research Report) today and set a price target of $7.00...

Buy Rating Affirmed for Prelude Therapeutics on Strong Pipeline and Financial Position

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Barclays Reaffirms Their Sell Rating on Prelude Therapeutics (PRLD)

Morgan Stanley analyst Jeffrey Hung maintained a Sell rating on Prelude Therapeutics (PRLD – Research Report) today and set a price target of $4.00...

Prelude Therapeutics (PRLD) Receives a Sell from Morgan Stanley

H.C. Wainwright analyst Robert Burns reiterated a Hold rating on Prelude Therapeutics (PRLD – Research Report) today and set a price target of $5.0...

Hold Rating on Prelude Therapeutics Pending Phase 1 Results of PRT3789

The latest update is out from Prelude Therapeutics ( ($PRLD) ). Prelude Therapeutics has announced its presentation of clinical data on PRT3789, a ...

Prelude Therapeutics Unveils Promising Cancer Treatment Data at ESMO

Analyst Robert Burns of H.C. Wainwright reiterated a Hold rating on Prelude Therapeutics (PRLD – Research Report), retaining the price target of $5...

Hold Rating on Prelude Therapeutics Pending PRT3789 Trial Results

Jeffrey Hung, an analyst from Morgan Stanley, maintained the Sell rating on Prelude Therapeutics (PRLD – Research Report). The associated price tar...

Prelude Therapeutics: Uncertainties in Drug Efficacy and Dosing Prompt Sell Rating

In a report released today, Reni Benjamin from JMP Securities reiterated a Buy rating on Prelude Therapeutics (PRLD – Research Report), with a pric...

Buy Rating Affirmed for Prelude Therapeutics on Promising PRT3789 Trial Results and Strong Financial Position

In a report released today, Peter Lawson from Barclays assigned a Sell rating to Prelude Therapeutics (PRLD – Research Report), with a price target...

Prelude Therapeutics (PRLD) Gets a Sell from Barclays

In a report released today, Robert Burns from H.C. Wainwright reiterated a Hold rating on Prelude Therapeutics (PRLD – Research Report), with a pri...

Hold Rating on Prelude Therapeutics Amid Cautious Optimism for PRT3789's Early Promise

PRLD

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Prelude Therapeutics to Participate in Barclays Global Healthcare Conference

Health Care

Prelude Announces Acceptance of Multiple Preclinical Abstracts at the 2024 AACR Annual Meeting

Prelude Highlights Continued Strength of Discovery Engine at 2024 AACR Annual Meeting

Prelude Therapeutics Reports First Quarter 2024 Financial Results and Provides Corporate Update

Prelude Therapeutics to Participate in Citizens JMP Life Sciences Conference

Prelude Therapeutics to Participate in Upcoming Healthcare Conferences

Prelude Therapeutics Announces Clinical Collaboration with Merck to Evaluate PRT3789 in Combination with KEYTRUDA® (pembrolizumab) in Patients with SMARCA4-Mutated Cancers

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